ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
Select the sulfonamide drug which is active against pseudomonas and is used by topical application for prophylaxis of infection in burn cases
Correct Answer: B
Rationale: Silver sulfadiazine is used topically for burn prophylaxis, effective against Pseudomonas due to its broad-spectrum activity.
Question 2 of 5
Nalidixic acid is primarily active against
Correct Answer: D
Rationale: Nalidixic acid is primarily active against gram-negative bacteria, especially in the urinary tract.
Question 3 of 5
Which of the following is not a first line antitubercular drug?
Correct Answer: A
Rationale: Ciprofloxacin is not a first-line TB drug; first-line drugs include isoniazid, rifampin, pyrazinamide, ethambutol, and streptomycin.
Question 4 of 5
Which of the following chemotherapy agents acts by intercalation?
Correct Answer: C
Rationale: Doxorubicin intercalates DNA, inhibiting nucleic acid synthesis.
Question 5 of 5
The most important reason for using a combination of chemotherapeutic agents in the treatment of tuberculosis is
Correct Answer: B
Rationale: Preventing resistance is the primary reason for TB combination therapy, targeting different bacterial populations.