ATI RN
Clinical Pharmacology of Cardiovascular Drugs PPT Questions
Question 1 of 5
Select the brain and spinal cord regions which are involved in the transmission of pain?
Correct Answer: D
Rationale: The correct answer is D because all of the mentioned regions are involved in the transmission of pain. The limbic system processes emotions related to pain. The thalamus relays sensory information to the cortex. The substantia gelatinosa in the spinal cord regulates pain signals. Each region plays a crucial role in the pain pathway, from perception to emotional response. Choices A, B, and C are incorrect because each region mentioned is directly involved in pain transmission.
Question 2 of 5
The mechanism of haloperidol antipsychotic action is:
Correct Answer: A
Rationale: The correct answer is A: Blocking D2 receptors. Haloperidol is a typical antipsychotic that primarily works by blocking dopamine D2 receptors in the brain, leading to a reduction in dopamine activity and alleviating psychotic symptoms. Choices B and C are incorrect as haloperidol does not primarily act by central alpha-adrenergic blocking or inhibition of norepinephrine uptake mechanisms. Choice D, "All of the above," is incorrect as haloperidol's main mechanism of action is through D2 receptor blockade, not through all the mechanisms listed.
Question 3 of 5
Which of the following agents is a respiratory analeptic?
Correct Answer: C
Rationale: Step-by-step rationale for why choice C (Bemegride) is correct: 1. Bemegride is a respiratory analeptic that stimulates the respiratory center in the brain. 2. It acts as a central nervous system stimulant, specifically targeting the respiratory system. 3. Bemegride is used to treat respiratory depression caused by drug overdose or anesthesia. 4. It helps increase respiratory rate and tidal volume by stimulating the brainstem. 5. Therefore, Bemegride is the correct choice as a respiratory analeptic. Summary of why other choices are incorrect: A: Piracetam is a nootropic drug that enhances cognitive function, not a respiratory analeptic. B: Sydnocarb is a psychostimulant used for attention deficit disorders, not a respiratory analeptic. D: Pantocrin is a medication derived from deer antlers used for various health benefits, not a respiratory analeptic.
Question 4 of 5
In contrast to benzodiazepines,buspirone:
Correct Answer: C
Rationale: Rationale for correct answer (C): 1. Buspirone is a serotonin receptor agonist and does not directly interact with the GABAergic system. 2. Buspirone is not associated with marked hypnotic, anticonvulsant, or muscle relaxant properties. 3. Studies show that buspirone causes less psychomotor impairment and does not affect driving skills. 4. Therefore, choice C is correct as it accurately contrasts buspirone from benzodiazepines. Summary of incorrect choices: A. Benzodiazepines interact with the GABAergic system, not buspirone. B. Benzodiazepines have hypnotic, anticonvulsant, and muscle relaxant properties, not buspirone. D. Buspirone has minimal abuse liability compared to benzodiazepines, which have high abuse potential.
Question 5 of 5
Which of the following inhaled anesthetics causes centrally mediated sympathetic activation leading to a rise in blood pressure and heart rate?
Correct Answer: A
Rationale: Desflurane is the correct answer because it causes sympathetic activation by stimulating the central nervous system, leading to increased blood pressure and heart rate. Desflurane has a high potency in activating sympathetic responses compared to the other options. Sevoflurane and isoflurane have minimal impact on sympathetic activation. Nitrous oxide primarily acts as a weak anesthetic and does not cause significant sympathetic stimulation.