ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
Secrete cytokines if damaged
Correct Answer: D
Rationale: Living skin keratinocytes secrete cytokines when damaged as an innate response.
Question 2 of 5
Makes integrins more 'sticky'
Correct Answer: D
Rationale: Chemokines activate integrins to enhance adhesion.
Question 3 of 5
Parasitic worm eggs are resistant to low pH and proteolytic digestion in the stomach. Adult worms living inside the lower gut are protected from many of the components of the immune response. Mast cells respond to worms. What immunoglobulin activates these mast cells, leading to degranulation?
Correct Answer: C
Rationale: IgE is the key immunoglobulin involved in allergic and parasitic responses, binding to mast cells and triggering degranulation to combat worms.
Question 4 of 5
Natural killer cells are thought to fill the gap between initial innate response and adaptive immune response. They evolved to detect low levels of MHC caused by the diseases of and
Correct Answer: C
Rationale: NK cells detect reduced MHC class I expression, common in herpes virus infections and tumor cells, bridging innate and adaptive immunity.
Question 5 of 5
Subunit vaccines contains components from pathogens, which are inactivated and referred to as These vaccines are generally of low immunogenicity and may need to work effectively.
Correct Answer: D
Rationale: Subunit vaccines use toxoids or antigens and require adjuvants to boost immunogenicity.