Sara S. is a 41-year-old patient who has just had a bone marrow transplant. The AGACNP knows that which medication will be used to decrease her risk of graft-versus-host reaction?

Correct Answer: A

Rationale: The correct answer is A: Immune globulin. Post bone marrow transplant, immune globulin is used to decrease the risk of graft-versus-host reaction by providing passive immunity. This helps in reducing the chances of the donor's immune cells attacking the recipient's tissues. Immune globulin does not suppress the immune system like cyclosporine (B) or systemic corticosteroids (D) do, which could increase the risk of infections post-transplant. Prophylactic antibiotics (C) are used to prevent infections but do not specifically target graft-versus-host reaction.

Correct Answer: C

Rationale: The correct answer is C: Hyperemesis gravidarum. This condition is characterized by severe nausea, vomiting, weight loss, dehydration in pregnancy. It is more severe than typical morning sickness (choice A) and is not specific to multiple gestation (choice B). Hypertensive disorders (choice D) typically present with high blood pressure, proteinuria, and edema, not just nausea and vomiting. Hyperemesis gravidarum requires medical intervention due to potential complications from dehydration and malnutrition.

Correct Answer: B

Rationale: The correct answer is B: Very severe anaemia. Productive cough, dyspnoea at rest, and generalized oedema are classic symptoms of very severe anaemia due to decreased oxygen-carrying capacity of the blood. Anemia leads to tissue hypoxia, causing shortness of breath and fluid retention. Folate deficiency (A) typically presents with megaloblastic anemia, not generalized edema. Mild iron deficiency (C) may lead to fatigue and weakness but not the severe symptoms described. Severe anemia (D) is too broad; very severe anemia specifically refers to the severity of the condition.

Correct Answer: C

Rationale: Step 1: In normal labor, the cervix undergoes effacement and dilation. Step 2: A short and thin cervical canal indicates progression towards labor. Step 3: Long and thick cervical canal suggests a delay in labor progress. Step 4: Choice C, short and thin cervical canal, is indicative of abnormal labor. Summary: A, B, and D do not reflect changes in the cervix seen in labor, making them incorrect choices.

Correct Answer: B

Rationale: The correct answer is B: Magnesium sulphate. It is the drug of choice for managing eclampsia due to its ability to prevent and control seizures. Magnesium sulfate acts as a central nervous system depressant and smooth muscle relaxant, helping to prevent further seizures. Phenobarbitone (A) is not the first-line treatment for eclampsia. Calcium gluconate (C) is used to counteract calcium channel blocker toxicity, not for eclampsia. Sodium bicarbonate (D) is used to treat metabolic acidosis, not eclampsia.