Sara S. is a 41-year-old patient who has just had a bone marrow transplant. The AGACNP knows that which medication will be used to decrease her risk of graft-versus-host reaction?

Correct Answer: B

Rationale: The correct answer is B: Cyclosporine. Cyclosporine is an immunosuppressant medication commonly used post-bone marrow transplant to prevent graft-versus-host disease. It works by inhibiting T-cell activation and proliferation, reducing the risk of the donor's immune cells attacking the recipient's tissues. Immune globulin (A) is used for passive immunization, not prevention of graft-versus-host reaction. Prophylactic antibiotics (C) are used to prevent infections post-transplant, not graft-versus-host disease. Systemic corticosteroids (D) may be used to treat graft-versus-host disease but are not the first-line prophylactic medication.

Correct Answer: B

Rationale: In the management of hypothermia neonatorum, the gradual rewarming process is aimed at preventing shock. Rapid rewarming can lead to vasodilation, causing a sudden drop in blood pressure and potentially leading to shock. Gradual rewarming helps the body adjust slowly to prevent this. Providing energy (Choice A) is not the primary goal of rewarming in hypothermia. Providing comfort (Choice C) is important but not the main purpose of the rewarming process. Preventing burns (Choice D) is not directly related to the rewarming process but is important to ensure the safety of the neonate during the rewarming process.

Correct Answer: C

Rationale: The correct answer is C: Seat belts. Flexion-distraction injuries of the thoracolumbar spine are commonly caused by seat belts due to the mechanism of injury during a motor vehicle accident. When a sudden deceleration occurs, the body is restrained by the seat belt while the spine continues to move forward, leading to hyperflexion of the spine. This results in distraction forces at the thoracolumbar junction, causing injury. Blunt trauma (choice A) can cause various types of spinal injuries but is not specifically associated with flexion-distraction injuries. Rotational injury (choice B) typically leads to injuries such as fractures or dislocations, not flexion-distraction injuries. Gunshot wounds (choice D) can cause direct spinal damage, but they do not typically result in flexion-distraction injuries.

Correct Answer: B

Rationale: The correct answer is B (3000 ml) because polyhydramnios is defined as an excessive amount of amniotic fluid, typically exceeding 2000-2500 ml. A level of 3000 ml is commonly used as a cutoff point for clinical diagnosis. Choices A, C, and D are incorrect because they fall below the threshold typically considered diagnostic for polyhydramnios. Answer A (1500 ml) is too low, while choices C (1900 ml) and D (2500 ml) are below or at the lower end of the range typically associated with polyhydramnios. Therefore, the most appropriate threshold for diagnosing polyhydramnios is when the amount of amniotic fluid exceeds 3000 ml.

Correct Answer: B

Rationale: The correct answer is B: Cyclosporine. Cyclosporine is an immunosuppressant medication commonly used post-bone marrow transplant to prevent graft-versus-host disease. It works by inhibiting T-cell activation and proliferation, reducing the risk of the donor's immune cells attacking the recipient's tissues. Immune globulin (A) is used for passive immunization, not prevention of graft-versus-host reaction. Prophylactic antibiotics (C) are used to prevent infections post-transplant, not graft-versus-host disease. Systemic corticosteroids (D) may be used to treat graft-versus-host disease but are not the first-line prophylactic medication.