Routine investigation of microbiological sanitary condition of air in a hospital is performed once in 3 months. What microorganism is the sanitary indicator of air condition in an enclosed space?

Correct Answer: D

Rationale: The correct answer is D: P.aeruginosa. This bacterium is commonly found in water and soil, making its presence in indoor air an indicator of poor sanitation. Step 1: P.aeruginosa is an opportunistic pathogen known to cause infections in hospitals. Step 2: Its presence in the air indicates potential contamination and poor air quality. Step 3: Regular monitoring of P.aeruginosa levels can help assess the effectiveness of sanitation measures. Summary: A, B, and C are not suitable indicators of air sanitation in an enclosed space as they are not typically associated with environmental contamination or poor air quality.

Correct Answer: A

Rationale: Rationale: 1. Epstein-Barr virus causes infectious mononucleosis due to primary infection. 2. Certain types of cancer, such as Burkitt lymphoma and nasopharyngeal carcinoma, are associated with Epstein-Barr virus through oncogenic mechanisms. 3. Chickenpox and shingles are caused by varicella-zoster virus (HHV3). 4. Roseola infantum is caused by human herpesvirus 6 (HHV6). Summary: Choice A is correct as Epstein-Barr virus is linked to infectious mononucleosis and specific cancers. Choices B, C, and D are incorrect as they are caused by different herpesviruses.

Correct Answer: A

Rationale: The correct answer is A, Clostridium botulinum. This bacterium produces botulinum toxin, leading to botulism. It is commonly found in soil and improperly canned food. Clostridium tetani causes tetanus, Staphylococcus aureus causes food poisoning, and Salmonella enterica causes salmonellosis. Therefore, A is correct due to its association with botulism, while the other choices are incorrect for causing different diseases.

Correct Answer: D

Rationale: The correct answer is D: BSL4. Ebola viruses are highly infectious and pose a high risk to laboratory workers. BSL4 facilities are designed to handle agents that pose a severe threat to human health and have no available vaccines or treatments. These facilities have strict guidelines for handling infectious agents, including full-body suits, negative air pressure, and decontamination processes to prevent any possible exposure. BSL1, BSL2, and BSL3 are not adequate for handling Ebola viruses due to their lower levels of containment and safety measures.

Correct Answer: A

Rationale: The correct answer is A because penicillins and cephalosporins inactivate transpeptidase activity of penicillin binding proteins, leading to disruption of bacterial cell wall synthesis. This mechanism makes them bactericidal, not bacteriostatic (choice B). Choice C is incorrect as penicillins and cephalosporins target cell wall synthesis, not the cytoplasmic membrane. Choice D is incorrect as option A is the correct statement.

Correct Answer: A

Rationale: The correct answer is A: prions. Prions are misfolded proteins that can cause spongiform encephalopathy by inducing normal proteins to misfold as well. Prions lack genetic material, distinguishing them from viruses (B), bacteria (C), and fungi (D), which all contain genetic material and cannot directly cause spongiform encephalopathy through protein misfolding.

Correct Answer: D

Rationale: The correct answer is D: Tuberculosis. Tuberculosis is considered a reemerging disease due to the increase in drug-resistant strains, high global prevalence, and challenges in diagnosis and treatment. This is supported by global health organizations' reports on the resurgence of TB cases. A: AIDS is not considered a reemerging disease as there has been significant progress in HIV prevention and treatment. B: Ebola outbreaks are sporadic and localized, not considered reemerging on a global scale. C: West Nile virus outbreaks occur periodically, but it is not considered a reemerging disease compared to TB.

Correct Answer: B

Rationale: The correct answer is B: Clostridium tetani. Clostridium tetani produces tetanospasmin, a neurotoxin causing tetanus. It enters the body through wounds and affects the nervous system. A: Clostridium botulinum produces botulinum toxin causing botulism, not tetanus. C: Streptococcus pneumoniae causes pneumonia, not tetanus. D: Mycobacterium tuberculosis causes tuberculosis, not tetanus.

Correct Answer: D

Rationale: The correct answer is D: Binary fission. Binary fission is a method of bacterial cell division, not a method of acquiring genetic material. Transformation, conjugation, and transduction are mechanisms through which bacteria can acquire genetic material from other sources. Transformation involves the uptake of naked DNA from the environment, conjugation is the transfer of genetic material through direct cell-to-cell contact, and transduction is the transfer of genetic material via bacteriophages. Therefore, binary fission is the only option that does not involve the acquisition of new genetic material.