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Question 1 of 5
Routes for transmission of nosocomial infections are
Correct Answer: D
Rationale: The correct answer is D because nosocomial infections can be transmitted through various routes, including air droplets, fecal-oral mechanism, contact mechanism, and parenteral mechanism. Air droplets can carry infectious agents through the air, while contact with contaminated surfaces or individuals can spread infections. Fecal-oral transmission occurs through ingesting contaminated food or water. Parenteral transmission involves the introduction of pathogens directly into the bloodstream. Therefore, all the options listed in D are correct routes for transmission of nosocomial infections. Choices A, B, and C are incorrect because they do not encompass all possible routes of transmission for nosocomial infections.
Question 2 of 5
After a prolonged isoniazid treatment, the patient developed polyneuritis, paresthesia, memory disorders, and convulsions. What is the most likely mechanism of the described isoniazid side-effects?
Correct Answer: D
Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions. A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects. B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis. C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.
Question 3 of 5
The structure used for bacterial motility is:
Correct Answer: C
Rationale: The correct answer is C: Flagella. Flagella are the structures used for bacterial motility, allowing bacteria to move towards or away from stimuli. They are long, whip-like appendages that rotate to propel the bacteria. Fimbriae (A) are short, hair-like structures used for attachment, not movement. Capsules (B) are protective layers surrounding bacteria. Pili (D) are used for adherence and conjugation, not motility. In summary, flagella are specifically designed for bacterial movement, making them the correct choice.
Question 4 of 5
A 47-year-old patient came to see a doctor on the 7th day of disease. The disease developed very fast: after the chill body temperature rose to 40oC and lasted up to 7 hours, then dropped abruptly, which caused profuse sweat. There were three such attacks occur in once in two days. Two days ago the patient arrived from Africa. Objectively: pale skin, subicteric sclera, significantly enlarged liver and spleen. What is the cause of fever attacks in this disease?
Correct Answer: A
Rationale: The correct answer is A: Erythrocytic schizogony. In this case, the patient most likely has malaria, specifically caused by Plasmodium falciparum. The fever attacks every 2 days (tertian fever) are characteristic of P. falciparum infection. The cycle of erythrocytic schizogony in P. falciparum is around 48 hours, leading to the recurring fever pattern. Choices B, C, and D are incorrect as tissue schizogony does not cause the characteristic fever pattern, exotoxins are not typically involved in malaria fever, and gametocytes do not directly cause fever attacks.
Question 5 of 5
In order to prevent wound infection associated with surgical procedures a patient was given a synthetic antiprotozoan drug with a high activity against Helicobacter pylori. Specify this drug:
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections. Incorrect choices: B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori. C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections. D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.
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