ATI RN
Intro to Pharmacology ATI Quizlet Questions
Question 1 of 5
Route of drug administration where the drug is placed directly into the GIT from where absorption occurs.
Correct Answer: A
Rationale: Enteral route of drug administration involves placing the drug directly into the gastrointestinal tract (such as oral or rectal routes) for absorption into the systemic circulation. This route requires the drug to pass through the digestive system before being absorbed, allowing for slower and more sustained release of the medication compared to other routes. Examples of enteral drug administration include oral tablets, capsules, and liquids as well as rectal suppositories.
Question 2 of 5
A patient is admitted to the hospital with multidrug-resistant urinary tract infection. Laboratory tests show Pseudomonas aeruginosa. Colistimethate sodium is ordered by intramuscular injection. The nurse understands that which of the following is the purpose for this drug?
Correct Answer: B
Rationale: Colistimethate sodium is a polymyxin antibiotic used to treat multidrug-resistant Gram-negative infections, including Pseudomonas aeruginosa. It is not safe for patients with renal impairments and does not prevent antibiotic resistance. Its primary purpose is to treat infections caused by resistant Gram-negative bacteria.
Question 3 of 5
The patient takes labetalol and is scheduled for surgery. The anesthesiologist plans to use halothane as one of the anesthetic agents. The nurse consults with the anesthesiologist to ensure awareness the patient’s medication history knowing that the combination of labetalol and halothane will have what effect?
Correct Answer: A
Rationale: There is increased risk of excessive hypotension if any of these drugs is combined with volatile liquid general anesthetics such as enflurane, halothane, or isoflurane. The effectiveness of diabetic agents is increased, leading to hypoglycemia when such agents are used with these drugs. Carvedilol has been associated with potentially dangerous conduction system disturbances when combined with verapamil or diltiazem. Vomiting is not associated with this combination of drugs. The nurse should communicate the patient’s medication history to the anesthesiologist to ensure safe administration of anesthesia.
Question 4 of 5
A patient is taking ibuprofen. The nurse understands that COX-1 and COX-2 inhibitors are different in that ibuprofen is more likely than celecoxib to cause which adverse effect?
Correct Answer: C
Rationale: Ibuprofen is a non-selective COX inhibitor, meaning it inhibits both COX-1 and COX-2 enzymes. COX-1 is responsible for maintaining the protective lining of the stomach, and its inhibition can lead to gastrointestinal adverse effects such as peptic ulcer disease. Celecoxib, on the other hand, is a selective COX-2 inhibitor, which primarily targets inflammation and pain without significantly affecting the stomach lining. Therefore, ibuprofen is more likely to cause peptic ulcer disease compared to celecoxib. This distinction is crucial for nurses to understand when managing patients on these medications, as it impacts patient monitoring and education.
Question 5 of 5
The nurse is reviewing the client's history who is about to take Methotrexate. Which of the following drugs can be safely administered together with methotrexate?
Correct Answer: B
Rationale: Folic acid supplementation is recommended for patients on methotrexate to reduce the risk of side effects such as mucositis and myelosuppression. Tetracycline, sulfamethoxazole, and phenytoin can interact with methotrexate, increasing its toxicity. Folic acid helps mitigate these adverse effects without interfering with the drug's efficacy.