ATI RN
Immune System Exam Questions Questions
Question 1 of 5
round, or oval shape that formed of 4 zones + central arteriole
Correct Answer: D
Rationale: White pulp is round/oval, has four zones (including PALS), and a central arteriole.
Question 2 of 5
Which of the following statements is correct about splenic sinusoids?
Correct Answer: B
Rationale: Splenic sinusoids are lined with elongated endothelial cells with large spaces ; Kupffer cells are in liver , stave cells line sinusoids (C is misphrased), basement membranes are discontinuous .
Question 3 of 5
An important effector function of antibodies is opsonization. Opsonized antigen can bind to Fc receptors on for instance macrophages. Which part of the antibody binds to the Fc receptor?
Correct Answer: C
Rationale: The Fc region (tail of heavy chains, C) binds Fc receptors on macrophages; Fab and antigen-binding parts bind antigens.
Question 4 of 5
What is the function of TAP1 and TAP2 proteins?
Correct Answer: B
Rationale: TAP1/2 transport cytosolic peptides into the ER for MHC I loading ; invariant chain and CLIP are MHC II-related.
Question 5 of 5
What cytokine does a Th1 cell produce that influences B cells during class switching to produce IgG3?
Correct Answer: C
Rationale: IFN-γ from Th1 cells drives IgG3 class switching ; IL-4 favors IgE, TNF and IL-2 have other roles.