ATI RN
microbiology chapter 13 test bank Questions
Question 1 of 5
Rotaviruses:
Correct Answer: A
Rationale: The correct answer is A because the NSP4 nonstructural protein of rotaviruses indeed acts in a toxic-like manner by disrupting calcium homeostasis, leading to diarrhea. Choice B is incorrect as rotaviruses can cause significant disease in infants, but not typically in adults. Choice C is incorrect as rotaviruses are resistant to stomach acid. Choice D is incorrect as rotaviruses cause a net secretion of water and loss of ions, contributing to diarrhea.
Question 2 of 5
Which description matches most to adenoviruses:
Correct Answer: A
Rationale: Step-by-step rationale: 1. Adenoviruses are DNA viruses, so choices B and C (ssRNA and DNA) are incorrect. 2. Adenoviruses have a middle-sized, naked icosahedral capsid, making choice A the correct description. 3. Choice D is incorrect as adenoviruses do have specific characteristics, making "None of the above" an inaccurate option. In summary, the correct answer A is supported by the fact that adenoviruses have a middle-sized, naked icosahedral capsid and contain double-stranded DNA. Choices B, C, and D are incorrect as they do not align with the characteristics of adenoviruses.
Question 3 of 5
Young man is hospitalized in pulmonology with complaints of dry cough, fatigue and suffocations. The anamnesis and the lab tests lead to pneumocystis pneumonia. The CD4+ cells are less than 200/mm3. What test you will order:
Correct Answer: B
Rationale: The correct answer is B: For HIV. Pneumocystis pneumonia in a young man with CD4+ cells less than 200/mm3 is highly suggestive of HIV infection. HIV weakens the immune system, leading to opportunistic infections like pneumocystis pneumonia. Testing for HIV is crucial for diagnosis and appropriate management. Explanation for other choices: A: Testing for ureaplasma urealyticum is not indicated in this case as the symptoms and CD4+ cell count point towards an HIV-related infection. C: Testing for Treponema pallidum (syphilis) is not relevant in the context of a young man with pneumocystis pneumonia and low CD4+ cell count. D: Testing for Neisseria gonorrhoea is not appropriate in this scenario as the symptoms and CD4+ cell count suggest an underlying HIV infection rather than a bacterial sexually transmitted infection.
Question 4 of 5
The most important virulence factor of Neisseria meningitidis is:
Correct Answer: B
Rationale: The correct answer is B: Polysaccharide capsule. The capsule of Neisseria meningitidis is crucial for its virulence as it helps the bacteria evade the host immune system by inhibiting phagocytosis. This allows the bacteria to survive and multiply in the host, leading to invasive infections. Exotoxins, beta-lactamase, and pyrogenic toxins are not the main virulence factors of Neisseria meningitidis and do not play as significant a role in its pathogenicity as the polysaccharide capsule.
Question 5 of 5
For measles virus is true that:
Correct Answer: B
Rationale: The correct answer is B: Contains single-stranded RNA with negative polarity. Measles virus is an enveloped virus with a single-stranded RNA genome that is negative-sense. This means it must first be transcribed into positive-sense RNA before it can be translated. Choice A is incorrect as the measles virus does have an outer envelope. Choice C is incorrect as measles virus belongs to the family Paramyxoviridae, not Togaviridae. Choice D is incorrect as measles virus can be grown on cell cultures, specifically on Vero cells.