Rifampin has the following unwanted effect:

Correct Answer: D

Rationale: Rifampin is known to cause hepatotoxicity, making option D the correct answer. Rifampin is metabolized in the liver, potentially leading to liver damage. The other options, dizziness and headache (A), loss of hair (B), and flu-like syndrome with tubular necrosis (C), are not commonly associated with rifampin use. Hepatotoxicity is a serious adverse effect that warrants close monitoring during rifampin therapy.

Correct Answer: D

Rationale: The correct answer is D: Triamterene. Triamterene is a potassium-sparing diuretic, which means it helps retain potassium in the body. In familial hypokalemic periodic paralysis, there is already low potassium levels, so giving a potassium-sparing diuretic like triamterene could further decrease potassium levels and worsen the condition. Mannitol (A) is an osmotic diuretic, Hydrochlorothiazide (B) is a thiazide diuretic, and Ethacrynic acid (C) is a loop diuretic, all of which can cause potassium loss and exacerbate hypokalemia in this patient.

Correct Answer: D

Rationale: The correct answer is D: Acetazolamide. This medication is a carbonic anhydrase inhibitor commonly used to treat glaucoma and altitude sickness. It can cause depression as a side effect. Mannitol (A) is an osmotic diuretic, Latanoprost (B) and Timolol (C) are both glaucoma medications that do not typically cause depression. Therefore, Acetazolamide is the most likely culprit for the symptoms in the depressed man.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.