ATI RN
Pharmacology ATI Final Questions
Question 1 of 5
Rho(D) immune globulin (RhoGAM) is given to a pregnant woman after delivery and the nurse is giving information to the patient about the indication of the medication. The nurse determines that the patient understands the purpose of the medication if the patient tells that it will protect her baby from which of the following?
Correct Answer: D
Rationale: Rho(D) immune globulin (RhoGAM) is administered to Rh-negative mothers to prevent Rh incompatibility in future pregnancies. It works by preventing the mother's immune system from developing antibodies against Rh-positive fetal blood cells, which could harm subsequent Rh-positive babies. Pernicious anemia and German measles are unrelated to RhoGAM. The medication does not affect the baby's blood type but prevents the mother's immune response. Therefore, Rh incompatibility is the correct answer.
Question 2 of 5
Regarding opioids:
Correct Answer: C
Rationale: Neonates have an immature blood-brain barrier, increasing opioid penetration, not blocking it, so that's false. Spinal analgesia involves mu, delta, and kappa receptors, not just one type, making that false. Depressed CO2 response is the most reliable sign of opioid-induced respiratory depression, a true statement, reflecting medullary suppression. Tolerance to miosis develops minimally, unlike analgesia, so that's false. Addison's patients are hypersensitive to opioids due to cortisol lack. The CO2 response is a key monitoring parameter in opioid overdose.
Question 3 of 5
A client with benign prostatic hyperplasia is to receive finasteride (Proscar). The nurse understands that this drug works by
Correct Answer: B
Rationale: Finasteride (Proscar), a 5-alpha reductase inhibitor, shrinks the prostate in BPH by reducing dihydrotestosterone, easing urinary obstruction. Smooth muscle relaxation is for ED drugs like sildenafil. It lowers DHT, not testosterone, and doesn't stimulate RNA synthesis. Prostate shrinkage is its core action, distinct from other mechanisms.
Question 4 of 5
The student nurse has been reading about the Human Genome Project and asks the nursing instructor how this will impact future pharmacological therapies. What is the best response by the instructor?
Correct Answer: D
Rationale: The Human Genome Project enables pharmacogenomics, tailoring drugs to genetic profiles for better efficacy (e.g., CYP2D6 variants), not eliminating drugs. Standardized doses ignore genetics. Disease prevention via genes complements, not replaces, drugs. Individualized therapy leverages genomics, enhancing treatment precision.
Question 5 of 5
Which common adverse effects of selective serotonin reuptake inhibitors (SSRIs) would be stressed by the nurse during patient discharge?
Correct Answer: B
Rationale: SSRIs (e.g., sertraline) commonly cause weight gain and sexual dysfunction (e.g., delayed ejaculation), per patient reports-key for adherence. Drowsiness/coma are overdose risks, not common. Headache/nausea occur but fade. Dry mouth/urine retention are anticholinergic, not SSRI. These impact quality of life, needing emphasis.