Rheumatoid factor (RF) positivity in individuals with extra-articular manifestations is almost exclusively occur in RF-positive polyarthritis characterized by aggressive manifestation that is almost exclusively occurs in symmetrical arthritis of both upper and lower extremities. Which of the following is NOT correlated with ANA positivity?

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Question 1 of 5

Rheumatoid factor (RF) positivity in individuals with extra-articular manifestations is almost exclusively occur in RF-positive polyarthritis characterized by aggressive manifestation that is almost exclusively occurs in symmetrical arthritis of both upper and lower extremities. Which of the following is NOT correlated with ANA positivity?

Correct Answer: D

Rationale: Age and gender are strongly correlated with ANA positivity, while uveitis is a common extra-articular manifestation.

Question 2 of 5

One of the following can cause thrombocytopenia with decreased megakaryocytes in bone marrow:

Correct Answer: B

Rationale: Aplastic anemia results from bone marrow failure, leading to pancytopenia, including decreased megakaryocytes, which causes thrombocytopenia. Other causes, such as ITP and hypersplenism, typically have normal or increased megakaryocytes.

Question 3 of 5

A 14-year-old boy develops a youth violence that has been started 6 months ago. The parents are asking about the factors that may increase the risks for serious violence. Of the following, the MOST important risk factor for development of serious youth violence in this boy is

Correct Answer: C

Rationale: Association with antisocial delinquent friends can significantly increase the risk of serious violence by reinforcing aggressive behaviors and norms.

Question 4 of 5

Skin biopsy for diagnosis of possible urticarial vasculitis is recommended for

Correct Answer: A

Rationale: Urticarial vasculitis presents as lesions persisting longer than 24 hours, often with purpura, requiring biopsy to differentiate from chronic urticaria.

Question 5 of 5

What is a consequence of deforestation?

Correct Answer: D

Rationale: Deforestation leads to the loss of biodiversity as it destroys natural habitats for countless species, disrupting ecosystems.

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