ATI RN
ATI Capstone Pharmacology Assessment Questions
Question 1 of 5
Reye's syndrome, a potentially fatal illness associated with liver failure and encephalopathy is associated with the administration of which over-the-counter (OTC) medication?
Correct Answer: C
Rationale: Reye's syndrome is linked to the use of aspirin in children and adolescents, particularly during viral infections. It causes severe liver and brain damage. Acetaminophen, ibuprofen, and antihistamines are not associated with this condition. Avoiding aspirin in pediatric patients is critical to prevent this rare but life-threatening syndrome.
Question 2 of 5
When giving a patient Lithium what is a life threatening side effect?
Correct Answer: C
Rationale: One life-threatening side effect of lithium therapy is the risk of seizures. While seizures are a rare side effect, they can occur, especially at higher doses or in patients with a history of seizure disorders. It is important to monitor for any signs of seizures in patients taking lithium and to promptly address any potential neurological symptoms.
Question 3 of 5
Penicillin's effectiveness against rapidly growing cell is primarily due to its effect on what?
Correct Answer: C
Rationale: Penicillin is a type of antibiotic that works by disrupting the synthesis of the bacterial cell wall. Bacterial cells have a cell wall that provides structural support and protection. The cell wall is composed of peptidoglycan, a complex molecule that gives the cell wall its strength. Penicillin interferes with the formation of peptidoglycan by inhibiting the enzyme transpeptidase, which is essential for cross-linking the peptidoglycan strands. As a result, bacterial cells become more susceptible to osmotic pressure and eventually burst, leading to their death. This mechanism of action is particularly effective against rapidly growing bacterial cells because they are actively synthesizing new cell wall components to keep up with their growth. Thus, penicillin's primary effectiveness against rapidly growing cells is primarily due to its disruption of cell wall synthesis.
Question 4 of 5
Which of the following should be monitored for patients taking diuretics? (select all that apply)
Correct Answer: A
Rationale: A. Daily weight should be monitored for patients taking diuretics because diuretics can cause fluid loss which may lead to weight changes. Fluctuations in weight can indicate changes in fluid balance and help determine the effectiveness of the diuretic therapy.
Question 5 of 5
What is the pharmacological action of meç€æ˜€ormin?
Correct Answer: A
Rationale: Metformin belongs to the class of medications known as biguanides. Biguanides work primarily by decreasing glucose production in the liver and increasing insulin sensitivity in peripheral tissues, such as muscles. They also help improve glucose uptake and utilization by cells, leading to better control of blood sugar levels. Metformin is commonly used to treat type 2 diabetes mellitus and can also be used in the management of polycystic ovary syndrome (PCOS).