ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
Regarding the cutaneous immune system (skin), T lymphocytes and Langerhans cells (chiefly ) are found in the and macrophages and T cells are found in the
Correct Answer: D
Rationale: Langerhans cells (DCs) and CD8+ T cells are in the epidermis; macrophages and T cells are in the dermis.
Question 2 of 5
B cells whose BCRs bind antigen with high-affinity receive survival signals (called selection) from follicular dendritic cells (FDCs) and germinal center T cells, whereas those that fail to bind antigen
Correct Answer: B
Rationale: High-affinity B cells undergo positive selection and survive; low-affinity cells die.
Question 3 of 5
Which of the following begins at the DP stage and not the DN stage?
Correct Answer: A
Rationale: α chain rearrangement occurs at the DP stage, while β chain rearrangement happens earlier at the DN stage.
Question 4 of 5
Cytokines produced by TH1 are ___ (microbial infection response) and cytokines produced by TH2 are ___ (parasitic infection response and allergy response).
Correct Answer: A
Rationale: TH1 produces IFN-γ and TNF-β for microbial defense; TH2 produces IL-4 and IL-5 for parasites/allergies.
Question 5 of 5
Which of the following best describes the affinity of antibody secreted for effector B cells?
Correct Answer: C
Rationale: Affinity increases during the immune response due to affinity maturation in effector B cells.