ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Regarding ketamine, which statement is true?
Correct Answer: D
Rationale: Ketamine can increase heart rate and is contraindicated in conditions like sick sinus syndrome.
Question 2 of 5
The following receptors are affected by antipsychotic drugs EXCEPT:
Correct Answer: C
Rationale: Antipsychotics (e.g., haloperidol) block central D2 (choice A) and 5-HT2 receptors (choice B) for efficacy, and muscarinic receptors (choice D) peripherally, causing side effects. Peripheral H2 receptors (choice C), involved in gastric acid secretion, aren't significantly affected; H1 antagonism occurs instead. This exception clarifies antipsychotic receptor profiles.
Question 3 of 5
Trichloroethanol is the active metabolite of:
Correct Answer: D
Rationale: Chloral hydrate (choice D) is metabolized to trichloroethanol, which depresses the CNS, inducing sedation. Morphine (choice A) metabolizes to active compounds like morphine-6-glucuronide, not trichloroethanol. Clorazepate (choice B) becomes desmethyldiazepam, a benzodiazepine. Phenobarbitone (choice C) is a barbiturate, not metabolized to trichloroethanol. This identifies Chloral hydrate's metabolic pathway, key for its hypnotic use.
Question 4 of 5
Anti-epileptic, chemically derived from the tricyclic antidepressant is
Correct Answer: A
Rationale: Carbamazepine is a tricyclic antidepressant derivative that is commonly used in the treatment of epilepsy especially for focal and generalized tonic-clonic seizures.
Question 5 of 5
Choose the correct statement from the following
Correct Answer: C
Rationale: Picrotoxin is a GABA-A receptor antagonist that blocks chloride channels, leading to convulsant effects.