ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Regarding GABA, which statement is false?
Correct Answer: A
Rationale: GABA receptor blockers typically have proconvulsant activity rather than anticonvulsant effects.
Question 2 of 5
Which of the following drugs was most likely prescribed for the 44-year-old woman with poorly controlled simple partial seizures that was only partially effective with valproic acid therapy?
Correct Answer: D
Rationale: The recently approved drug that acts with a novel mechanism of action, a noncompetitive blockade of AMPA receptors on brain neurons, is Perampanel. Given that the patient had poorly controlled seizures with valproic acid, adding Perampanel would provide a different mechanism of action to improve seizure control.
Question 3 of 5
Epinephrine HCl has little or no effect on
Correct Answer: A
Rationale: Epinephrine is poorly absorbed through unbroken skin but is effective on mucosal surfaces.
Question 4 of 5
A 21-year-old woman presents to her primary care physician complaining of “feeling sleepy all the time.†Physical exam is normal, but she has a history of hay fever since she was 14 years old. You discover that she is currently taking medicine for her allergy but cannot remember the name. She says it controls her hay fever symptoms well. You suspect that her medication is causing her to feel sleepy. Which of the following would be most likely to cause drowsiness?
Correct Answer: C
Rationale: Doxylamine, an antihistamine, is known to cause drowsiness due to its sedative effects on the central nervous system.
Question 5 of 5
Diazoxide is an effective hypotensive, but it is not used long-term because
Correct Answer: D
Rationale: Diazoxide has multiple adverse effects including hyperglycemia fluid retention and hyperuricemia.