ATI RN
Pediatric Immunity NCLEX Questions Questions
Question 1 of 5
Regarding chemokines, which one of the following is the most accurate?
Correct Answer: C
Rationale: Chemokines, like IL-8, attract neutrophils to infection sites, aiding inflammation.
Question 2 of 5
Which immune system cells recognize body cells with reduced expression of MHC class I molecules?
Correct Answer: D
Rationale: NK cells target cells with low MHC I, a sign of viral infection or malignancy.
Question 3 of 5
A 6-month-old presents with recurrent cellulitis and bacteremias due to Staphylococcus aureus. The white blood cell count is 2500 with 5% neutrophils, 10% eosinophils, 35% monocytes, and 50% lymphocytes. The platelet count is 650,000. A brother and a female cousin died at the age of 18 months and 2 years, respectively. The most likely diagnosis is
Correct Answer: C
Rationale: Kostmann disease (severe congenital neutropenia) fits with persistent neutropenia, recurrent Staphylococcus aureus infections, and a family history suggesting autosomal recessive inheritance.
Question 4 of 5
In addition to infection and bleeding, the MOST common cause of death in Wiskott-Aldrich syndrome is
Correct Answer: D
Rationale: Wiskott-Aldrich syndrome (WAS) patients have a high risk of EBV-associated lymphomas due to immune dysregulation, making it a leading cause of death.
Question 5 of 5
Chronic neutropenia by definition lasts longer than
Correct Answer: B
Rationale: Chronic neutropenia is defined as lasting >3 months, distinguishing it from transient causes like viral infections.