Raynaud phenomenon (RP) associated with rheumatic disease (RD) is usually consistent with RD rather than RP. The feature that is MOST likely consistent with RD rather than RP is

Correct Answer: A

Rationale: Periungual tissue necrosis is a significant indicator of underlying connective tissue disease.

Correct Answer: C

Rationale: Histamine is a primary mediator released from mast cells during allergic reactions.

Correct Answer: A

Rationale: At 12 months, children are able to pull to standing and walk holding on or independently. Large push-pull toys for kinesthetic stimulation would be appropriate and beneficial for this age group.

Correct Answer: B

Rationale: Ventricular septal defect (VSD) is the most common congenital heart defect in neonates. VSDs involve a hole in the wall separating the heart’s ventricles and may lead to heart failure if untreated.

Correct Answer: C

Rationale: Renal tubular acidosis typically causes normal anion gap metabolic acidosis rather than an increased anion gap.