Radioactive iodine is the treatment of choice for the following category of thyrotoxic patients:

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Chapter 14 Drugs for the Reproductive System Questions

Question 1 of 5

Radioactive iodine is the treatment of choice for the following category of thyrotoxic patients:

Correct Answer: B

Rationale: The correct answer is B: Young adults with recent onset of Grave's disease. Radioactive iodine is the treatment of choice for this category of thyrotoxic patients because it effectively destroys the overactive thyroid tissue, providing a long-term solution. Children are not typically treated with radioactive iodine due to concerns about potential long-term effects on growth and development. Elderly patients with ischaemic heart disease may not be suitable candidates due to the risk of exacerbating heart conditions. Pregnant women should not receive radioactive iodine treatment as it can harm the developing fetus. Therefore, the most appropriate choice is B based on the effectiveness and safety considerations for each category of patients.

Question 2 of 5

In diabetic patients, round the clock tight control of hyperglycaemia achieved by multiple daily insulin injections or insulin pumps:

Correct Answer: C

Rationale: Step 1: Tight control of hyperglycemia in diabetic patients aims to reduce complications. Step 2: Multiple daily insulin injections or insulin pumps can lead to hypoglycemia. Step 3: Hypoglycemic reactions are associated with tight control methods. Step 4: Therefore, option C is correct as it highlights the higher incidence of hypoglycemic reactions with round-the-clock tight control.

Question 3 of 5

Which of the following measures is not an essential component of the management of moderately severe diabetic ketoacidosis:

Correct Answer: D

Rationale: The correct answer is D: Sodium bicarbonate. In diabetic ketoacidosis, the blood becomes acidic due to ketone accumulation. Administering sodium bicarbonate can worsen the acidosis by shifting the pH too rapidly. Insulin is essential to lower blood glucose levels, IV fluids are necessary to correct dehydration, and potassium chloride is needed to replenish electrolytes. Sodium bicarbonate is not recommended as it can lead to potential complications.

Question 4 of 5

Sulfonylureas do not lower blood sugar level in:

Correct Answer: A

Rationale: The correct answer is A. Sulfonylureas work by increasing insulin release from the pancreas, which helps lower blood sugar levels. Nondiabetics already have a properly functioning insulin system, so sulfonylureas would not have a significant impact on their blood sugar levels. In contrast, type 1 and type 2 diabetics have insulin deficiency or resistance, making them more responsive to sulfonylureas. Obese diabetics may also benefit from sulfonylureas as they can help improve insulin sensitivity. In summary, sulfonylureas are effective in individuals with diabetes but not in nondiabetics.

Question 5 of 5

Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus:

Correct Answer: D

Rationale: Rationale: Rosiglitazone is the correct answer as it is not a sulfonylurea but acts by a similar mechanism to enhance insulin sensitivity in peripheral tissues, unlike sulfonylureas that directly stimulate insulin release from pancreatic beta cells. Glimepiride, Repaglinide, and Miglitol are sulfonylureas or alpha-glucosidase inhibitors, which directly stimulate insulin release or delay carbohydrate absorption, respectively, making them unsuitable choices for the question.

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