Radical cure of vivax malaria should be attempted in

Correct Answer: D

Rationale: Radical cure for P. vivax (targeting hypnozoites) is advised in sporadic and controlled endemic areas to prevent relapse.

Correct Answer: D

Rationale: IV quinine can cause hypoglycemia by stimulating insulin release.

Correct Answer: A

Rationale: Pyrimethamine + sulfadoxine (Fansidar) is used as a clinical curative in chloroquine-resistant areas.

Correct Answer: C

Rationale: Mitoxantrone is a topoisomerase inhibitor, not a microtubule-affecting agent like the others.

Correct Answer: A

Rationale: Tinidazole, like metronidazole, is active against anaerobic bacteria.