ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Protein antigens bound to complement component C3d can bind simultaneously to both and the BCR. This enables the co-receptor complex to cluster and crosslink with the BCR, inducing phosphorylation.
Correct Answer: C
Rationale: C3d binds to CD21 (CR2), linking the co-receptor to the BCR for enhanced signaling.
Question 2 of 5
In the embryonic human, the primary lymphoid organs are initially in the yolk sac, then in the fetal , and finally in the
Correct Answer: D
Rationale: Hematopoiesis shifts from yolk sac to fetal spleen/liver, then bone marrow/thymus.
Question 3 of 5
Which of the following locations has cell that transport the antigens by transcytosis into sub-epithelial tissues (e.g. lamina propria) where they encounter lymphocytes?
Correct Answer: C
Rationale: Peyer's patches in GALT use M cells for transcytosis.
Question 4 of 5
Which of the following has the surface marker CD34 instead of the surface marker CD19, during B cell development?
Correct Answer: A
Rationale: CD34 is on hematopoietic stem cells; CD19 appears at the pro-B stage.
Question 5 of 5
Tolerance refers to the ability of B cells to:
Correct Answer: C
Rationale: B cell tolerance prevents reactivity to self-antigens.