ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
Protein and nucleic acid sequence data have been obtained for many TCRs with different specificities. Analyses of these sequences suggest the existence of how many hypervariable (hv) regions within the variable region?
Correct Answer: C
Rationale: TCRs have three hypervariable regions (CDR1, CDR2, CDR3) within their variable regions, similar to immunoglobulins.
Question 2 of 5
Adhesion molecule
Correct Answer: D
Rationale: CD11a (LFA-1) is an adhesion molecule that stabilizes T cell interactions.
Question 3 of 5
Which of the following MHC class II genes has the most alleles (most polymorphic)?
Correct Answer: D
Rationale: DRβ is the most polymorphic among MHC class II genes.
Question 4 of 5
Pemphigus vulgaris
Correct Answer: D
Rationale: Pemphigus vulgaris is associated with HLA-DQ2.
Question 5 of 5
Which of the following is NOT true of T-cell receptors, when compared to immunoglobulin?
Correct Answer: D
Rationale: TCRs do not undergo somatic hypermutation or class switching, unlike immunoglobulins.