Production of secreted antibodies (pAs site) involves a chain of amino acids with a stretch of charged (versus non charged) amino acids at the terminus, in comparison to membrane bound antibody production (pAm site).

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Pediatric Immunization NCLEX Questions Quizlet Questions

Question 1 of 5

Production of secreted antibodies (pAs site) involves a chain of amino acids with a stretch of charged (versus non charged) amino acids at the terminus, in comparison to membrane bound antibody production (pAm site).

Correct Answer: B

Rationale: Secreted antibodies have a shorter, charged COOH terminus compared to the longer, hydrophobic terminus of membrane-bound antibodies.

Question 2 of 5

Which of the following molecules is necessary (not accessory) for antigen recognition and T cell activation?

Correct Answer: B

Rationale: CD3 is essential for TCR signaling and T cell activation, unlike the accessory roles of CD4 and CD8.

Question 3 of 5

MHC class I has three genes (HLA-A, HLA-B, & HLA-C). Which of the following is the correct order from most alleles (most polymorphic) to least alleles?

Correct Answer: C

Rationale: HLA-B is the most polymorphic, followed by HLA-A, then HLA-C.

Question 4 of 5

Ankylosing spondylitis

Correct Answer: A

Rationale: Ankylosing spondylitis is strongly associated with HLA-B27.

Question 5 of 5

Directly: carbohydrate, protein, lipid, nucleic acid epitopes

Correct Answer: A

Rationale: Immunoglobulins directly recognize a wide range of epitopes.

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