Primary malignancies with the highest cumulative incidence of a second neoplasm are

Correct Answer: C

Rationale: Hodgkin disease survivors have the highest cumulative incidence of second malignancies due to chemotherapy and radiation exposure.

Correct Answer: A

Rationale: Repeated exposure to ophthalmic medications can lead to contact allergy, characterized by redness, swelling, and itching.

Correct Answer: A

Rationale: Prednisolone alone may be less effective for severe renal involvement.

Correct Answer: C

Rationale: Allergic asthma is a classic example of type I hypersensitivity, which involves IgE-mediated mast cell degranulation.

Correct Answer: D

Rationale: Hepatobiliary scintigraphy assesses bile flow and is crucial for diagnosing biliary atresia, the most common cause of neonatal cholestasis.