Primary immunodeficiencies are compromised states that result from genetic defects affecting 1 or more arms of the immune system while secondary immunodeficiencies result from infection, malignancy, or as an adverse effect of immunomodulating or immunosuppressing medications. Which of the following represent secondary immune deficiency?

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Pediatric Infectious Disease Questions

Question 1 of 5

Primary immunodeficiencies are compromised states that result from genetic defects affecting 1 or more arms of the immune system while secondary immunodeficiencies result from infection, malignancy, or as an adverse effect of immunomodulating or immunosuppressing medications. Which of the following represent secondary immune deficiency?

Correct Answer: B

Rationale: Cystic fibrosis leads to secondary immunodeficiency due to chronic infection.

Question 2 of 5

Toxic shock syndrome is an acute and potentially severe illness characterized by all the following EXCEPT

Correct Answer: C

Rationale: Focal neurologic abnormalities are not typical of toxic shock syndrome.

Question 3 of 5

In which of the following circumstances the diagnosis of acute rheumatic fever can be made without strict adherence to Jones criteria?

Correct Answer: D

Rationale: All listed scenarios allow diagnosis of rheumatic fever without strict Jones criteria adherence.

Question 4 of 5

Group B streptococcus (GBS), or Streptococcus agalactiae, is a major cause of neonatal bacterial sepsis. Of the following, the MOST common syndrome associated with childhood GBS disease beyond early infancy is

Correct Answer: A

Rationale: Bacteremia without a focus is the most common GBS syndrome beyond early infancy.

Question 5 of 5

The MOST common clinical manifestation of meningococcal infection is

Correct Answer: A

Rationale: Asymptomatic carriage is the most common meningococcal state.

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