ATI RN
Endocrinology Exam Questions and Answers Questions
Question 1 of 5
Postmenopausal estrogen therapy has been shown to increase a female's risk of all the following clinical outcomes except:
Correct Answer: B
Rationale: Postmenopausal estrogen therapy has been shown to have a protective effect on bone density and reduce the risk of osteoporosis-related fractures, including hip fractures. Estrogen therapy helps to maintain bone strength and reduce the chances of fractures in postmenopausal women. Therefore, estrogen therapy does not increase the risk of hip fractures; in fact, it may decrease the risk of hip fractures in this population.
Question 2 of 5
Which of the following is not a symptom of Cushing's syndrome?
Correct Answer: D
Rationale: Weight gain is a common symptom of Cushing's syndrome due to the excessive production of cortisol, a hormone that regulates metabolism and fat storage. The other symptoms listed, such as easy bruising, acne, and stretch marks, are also characteristic features of Cushing's syndrome. However, weight loss is typically not associated with this condition. In fact, individuals with Cushing's syndrome often experience unexplained and rapid weight gain, especially in the face, abdomen, and upper back (resulting in a characteristic "buffalo hump" appearance), rather than weight loss.
Question 3 of 5
Which of the following is the underlying problem in neurogenic diabetes insipidus?
Correct Answer: E
Rationale: Neurogenic diabetes insipidus is a condition characterized by a deficiency of vasopressin (antidiuretic hormone). Vasopressin is responsible for regulating the body's water balance by controlling the reabsorption of water in the kidneys. In neurogenic diabetes insipidus, there is a problem with either the production, release, or action of vasopressin, leading to excessive urination and thirst. This condition can be caused by damage to the hypothalamus or pituitary gland, which are involved in producing and releasing vasopressin. Symptoms of neurogenic diabetes insipidus include frequent urination, excessive thirst, and dehydration.
Question 4 of 5
Which one of the following statements describes the underlying pathology of Grave's disease?
Correct Answer: A
Rationale: Graves' disease is an autoimmune disorder where autoantibodies, known as thyroid-stimulating immunoglobulins (TSIs) or thyroid-stimulating antibodies (TSAs), bind to and stimulate the thyroid-stimulating hormone (TSH) receptors on thyroid follicular cells. This leads to increased production and secretion of thyroid hormones T3 (triiodothyronine) and T4 (thyroxine), causing hyperthyroidism. The autoantibodies essentially mimic the action of TSH, resulting in excess thyroid hormone release and manifestation of hyperthyroid symptoms. This underlying pathology of Graves' disease is distinct from other causes of hyperthyroidism, making choice A the correct statement.
Question 5 of 5
What is the most common cause for the overproduction of growth hormone in acromegaly?
Correct Answer: D
Rationale: Acromegaly is typically caused by the overproduction of growth hormone (GH) by the pituitary gland. In around 95% of cases, this overproduction is due to the presence of a non-cancerous tumor called a pituitary adenoma. These adenomas are benign, slow-growing tumors that cause the pituitary gland to produce excessive amounts of growth hormone, leading to the characteristic symptoms of acromegaly such as enlargement of the bones and soft tissues.