Plummer Vinson syndrome is not associated with:

Correct Answer: C

Rationale: The correct answer is C: clubbing. Plummer Vinson syndrome is characterized by the triad of dysphagia, iron deficiency anemia, and esophageal webs. Clubbing is not a typical feature of this syndrome. Angular stomatitis (A), splenomegaly (B), and post cricoid web (D) are all associated with Plummer Vinson syndrome. Angular stomatitis is due to iron deficiency anemia, splenomegaly can be present due to chronic anemia, and post cricoid web is a characteristic finding in the esophagus of patients with this syndrome.

Correct Answer: C

Rationale: Step 1: Hepato-splenomegaly with lymphadenopathy is commonly seen in hematologic malignancies. Step 2: Chronic Myeloid Leukemia (CML) primarily presents with splenomegaly, but not lymphadenopathy. Step 3: Acute Lymphoblastic Leukemia (ALL), lymphoma, and disseminated TB can all present with these findings. Step 4: Therefore, the correct answer is C - CML, as it does not typically present with lymphadenopathy. Other choices are incorrect as they can present with these symptoms.

Correct Answer: B

Rationale: The correct answer is B (3-4 days) because the half-life of platinum is known to be around 3-4 days based on scientific research and studies. This means that within this time frame, half of the amount of platinum will decay or disintegrate. The other choices (A, C, D) are incorrect because they do not align with the established half-life value of platinum. Option A (1-2 days), C (5-6 days), and D (7-8 days) do not fall within the typical range of platinum's half-life duration as determined by scientific data and experimentation. Therefore, option B is the most accurate and scientifically supported choice for the half-life of platinum.

Correct Answer: A

Rationale: The correct answer is A: Monitoring for infection. In patients with acute leukemia, the most common cause of death is infection due to the suppression of the immune system by the disease and its treatment. By closely monitoring for signs of infection such as fever, chills, increased heart rate, and low white blood cell count, the nurse can promptly intervene and provide appropriate treatment to prevent complications and improve patient outcomes. The other choices are incorrect because while they are important aspects of care for patients with leukemia, monitoring for infection directly addresses the most critical risk factor leading to mortality in this patient population.

Correct Answer: D

Rationale: The correct answer is D: ALL (Acute Lymphoblastic Leukemia). In this case, the patient's symptoms of severe headaches, vomiting, testicular pain, reduced blood cell counts, and high proportion of immature cells indicate a rapidly progressing hematologic malignancy affecting lymphoid cells. AML (Choice A) primarily affects myeloid cells, not lymphoid cells. CML (Choice B) is a chronic myeloid disorder and presents differently with elevated leukocyte count and mature cells. MDS (Choice C) is a group of disorders characterized by abnormal blood cell production, but the presentation in this patient is more indicative of an acute leukemia.