Pindolol oxprenolol have all of the following properties EXCEPT:

Correct Answer: B

Rationale: The correct answer is B because pindolol and oxprenolol are both partial agonists at beta-adrenergic receptors. This means they have intrinsic sympathomimetic activity. This property sets them apart from other beta blockers that do not have partial agonist activity. A: They are nonselective beta antagonists - True, they block both beta-1 and beta-2 receptors. C: They are less likely to cause bradycardia and abnormalities in plasma lipids - True, due to their partial agonist activity. D: They are effective in hypertension and angina - True, they are used for these conditions.

Correct Answer: B

Rationale: The correct answer is B: Carbamazepine. Carbamazepine is the first-line treatment for trigeminal neuralgia due to its efficacy in reducing nerve firing and alleviating neuropathic pain. It works by blocking sodium channels in neurons. Lamotrigine (A) is more commonly used for epilepsy. Topiramate (C) is effective for migraine prevention but less so for trigeminal neuralgia. Valproate (D) is not typically used for trigeminal neuralgia.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Opioid analgesics with affinity for the mu receptor exert their principal central nervous system effects through various mechanisms. 1. Analgesia: Opioids bind to mu receptors, inhibiting pain transmission in the CNS. 2. Respiratory depression: Stimulation of mu receptors in the brainstem suppresses the respiratory drive. 3. Euphoria: Activation of mu receptors in the limbic system can induce feelings of euphoria. Therefore, all these effects are collectively produced by opioids with mu receptor affinity. Other choices are incorrect because they do not encompass the comprehensive range of central nervous system effects associated with this class of analgesics.

Correct Answer: C

Rationale: The correct answer is C: Thromboembolism. Aspirin is commonly used prophylactically to prevent blood clots and reduce the risk of thromboembolic events, such as heart attacks and strokes. It inhibits platelet aggregation, making it effective in preventing clot formation. Noncardiogenic pulmonary edema (A), peptic ulcers (B), and metabolic acidosis (D) are not conditions for which aspirin is typically used prophylactically. Pulmonary edema is treated with diuretics, peptic ulcers with proton pump inhibitors, and metabolic acidosis with appropriate fluid and electrolyte management.

Correct Answer: D

Rationale: The correct answer is D: Fluoxetine. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) because it specifically targets the reuptake of serotonin in the brain, leading to increased levels of serotonin available for neurotransmission. Phenelzine (A) is a monoamine oxidase inhibitor, Desipramine (B) is a tricyclic antidepressant, and Maprotiline (C) is a tetracyclic antidepressant. These medications work through different mechanisms than SSRIs and do not specifically target serotonin reuptake. Therefore, they are not classified as SSRIs.