Phenothiazine derivatives are able to:

Correct Answer: A

Rationale: Phenothiazine derivatives are known to block dopamine receptors in the hypothalamus, leading to a decrease in body temperature, causing hypothermia (Choice A). Choices B, C, and D are incorrect because phenothiazines do not directly affect prolactin levels, corticotrophin release, pituitary growth hormone secretion, appetite, or weight. The mechanism of action of phenothiazines specifically targets the dopamine receptors to produce hypothermia.

Correct Answer: C

Rationale: The correct answer is C: Lorazepam. Lorazepam is less likely to cause cumulative and residual effects with multiple doses due to its shorter half-life compared to the other benzodiazepines listed. Its shorter half-life means it is metabolized and eliminated from the body more quickly, reducing the risk of accumulation and residual effects. Choice A, Clorazepate, is a prodrug with active metabolites that can lead to accumulation with repeated dosing. Choice B, Quazepam, has a long half-life which increases the risk of cumulative effects. Choice D, Prazepam, also has active metabolites that can accumulate over time, leading to residual effects.

Correct Answer: D

Rationale: Step 1: General anesthesia involves analgesia to block pain signals. Step 2: It causes loss of consciousness by inhibiting sensory and autonomic reflexes. Step 3: It induces amnesia to prevent memory formation during the procedure. Step 4: Therefore, all the elements - analgesia, loss of consciousness, and amnesia - are essential components of general anesthesia, making choice D the correct answer. Other choices are incorrect because they individually do not cover all the necessary aspects of general anesthesia.

Correct Answer: A

Rationale: Step 1: Zileutin is a leukotriene synthesis inhibitor. Step 2: Leukotrienes are inflammatory mediators produced by the body. Step 3: By inhibiting leukotriene production, zileutin reduces inflammation. Step 4: Therefore, the statement "Zileutin prevents the production of leukotrienes" is TRUE. Summary: Choice A is correct because zileutin indeed prevents the production of leukotrienes, leading to reduced inflammation. Choices B, C, and D are incorrect as they do not accurately reflect the mechanism of action of zileutin.

Correct Answer: A

Rationale: The correct answer is A, Filgrastim, as it is a granulocyte colony-stimulating factor used to stimulate the production of neutrophils. Filgrastim is commonly prescribed to increase white blood cell count in patients undergoing chemotherapy. Methotrexate (B) is a chemotherapy drug that does not stimulate granulocyte production. Erythropoietin (C) stimulates red blood cell production, not granulocytes. Doxorubicin (D) is an anthracycline antibiotic used in cancer treatment but does not stimulate granulocyte colony formation. Thus, the correct drug for granulocyte colony-stimulating factor is Filgrastim.