ATI RN
Pediatric Immunity NCLEX Questions Questions
Question 1 of 5
Persons with helminth infections mount immunologic responses that involve IgE and eosinophils. Which two cytokines are most important for these responses to occur?
Correct Answer: B
Rationale: IL-4 promotes IgE production, and IL-5 enhances eosinophil development and activation, both critical for immune responses against helminths.
Question 2 of 5
When a human pathogen is repeatedly grown and passaged in cells of a different species and then used for vaccination purposes, the resulting vaccine is referred to as a/an...?
Correct Answer: D
Rationale: Passaging a pathogen in a different species attenuates it, creating a live attenuated vaccine, as seen with some viral vaccines.
Question 3 of 5
The first immunoglobulin heavy chain class to be expressed on the surface of a newly produced B-cell is...?
Correct Answer: D
Rationale: IgM is the first immunoglobulin expressed on naive B cells, followed by co-expression with IgD during maturation.
Question 4 of 5
Long-term effective therapy for the patient described in Question 2 is best accomplished with
Correct Answer: B
Rationale: Interferon-γ is a standard long-term therapy for chronic granulomatous disease (CGD) as it enhances phagocyte function and reduces infection frequency. IVIG is used for antibody deficiencies, IL-2 for T-cell issues, and bone marrow transplantation for severe combined immunodeficiencies, not primarily for CGD.
Question 5 of 5
Matching: Immunodeficiency - Mandibular hypoplasia
Correct Answer: A
Rationale: DiGeorge syndrome includes facial anomalies like mandibular hypoplasia due to 22q11.2 deletion affecting branchial arch development.