Peripheral tolerance is maintained by all of the following mechanisms except

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Chapter 20 The Lymphatic System and Immunity Sample Questions Questions

Question 1 of 5

Peripheral tolerance is maintained by all of the following mechanisms except

Correct Answer: B

Rationale: Thymus deletion is central, not peripheral; anergy , clonal deletion , and Tregs are peripheral.

Question 2 of 5

In the above question, resolution of parasitic infections of the gastrointestinal tract is dependent upon the activation of:

Correct Answer: D

Rationale: Th2 cells drive IgE via IL-4/IL-13 for parasites; Th1 is antiviral, not IgG or cytotoxic .

Question 3 of 5

Which lymphoid organ shrinks significantly after puberty?

Correct Answer: B

Rationale: The thymus shrinks post-puberty; spleen , lymph nodes , and tonsils maintain size.

Question 4 of 5

Which lymphoid tissue is most active in early childhood?

Correct Answer: B

Rationale: The thymus is most active in childhood for T cell maturation; others (A, C, D) remain active throughout life.

Question 5 of 5

What is the role of the spleen's red pulp macrophages?

Correct Answer: C

Rationale: Red pulp macrophages remove old RBCs; antibodies are B cells, lymph is nodes, lymphocytes are white pulp.

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