ATI RN
ATI Pharmacology Made Easy 4.0 The Hematologic System Questions
Question 1 of 5
Peripheral adverse effects of levodopa, including nausea, hypotension, and cardiac arrhythmias, can be diminished by including which of the following drugs in the therapy?
Correct Answer: C
Rationale: Levodopa's peripheral conversion to dopamine by dopa decarboxylase causes nausea (via chemoreceptor trigger zone stimulation), hypotension, and arrhythmias. Carbidopa, a peripheral dopa decarboxylase inhibitor, prevents this conversion outside the CNS, reducing these side effects while increasing levodopa's brain availability. Amantadine, an NMDA antagonist, boosts dopamine release but doesn't address peripheral metabolism. Ropinirole, a dopamine agonist, bypasses levodopa but doesn't mitigate its effects. Tolcapone, a COMT inhibitor, prolongs levodopa's action but can increase peripheral dopamine if used alone, worsening side effects. Carbidopa's specific blockade of peripheral decarboxylation directly counters these adverse effects, making it the essential adjunct in levodopa therapy.
Question 2 of 5
The following are side effects of SSRI's EXCEPT:
Correct Answer: B
Rationale: SSRIs (e.g., fluoxetine) can cause rash as a hypersensitivity reaction, true. Weight gain isn't a hallmark side effect (unlike TCAs); some cause weight loss or neutrality, making this the exception, though key says B is true (possible typo). Sexual dysfunction (e.g., delayed ejaculation) is common, true. Anxiety can occur initially, true. GI symptoms like nausea are frequent. Per the key, weight gain isn't typical, distinguishing SSRIs from other antidepressants in side effect profiles.
Question 3 of 5
During an infusion of albumin, the nurse monitors the patient closely for the development of which adverse effect?
Correct Answer: C
Rationale: When administering an infusion of albumin (a colloid solution), the nurse must closely monitor the patient for signs and symptoms of fluid volume overload. This is because albumin infusion can lead to an excessive accumulation of fluid in the intravascular compartment, potentially causing volume overload. Symptoms of fluid volume overload may include dyspnea, crackles in the lungs, peripheral edema, increased blood pressure, and increased heart rate. Prompt recognition and intervention are essential to prevent complications such as pulmonary edema and heart failure. Monitoring for signs of fluid volume overload enables the nurse to adjust the infusion rate or take other appropriate actions to ensure the patient's safety.
Question 4 of 5
The nurse is providing education about the use of sublingual nitroglycerin tablets. She asks the patient, What would you do if you experienced chest pain while mowing your yard? You have your bottle of sublingual nitroglycerin with you. Which actions by the patient are appropriate in this situation? (Select all that apply.)
Correct Answer: A
Rationale: A. Stop the activity, and lie down or sit down: This is an appropriate action to take when experiencing chest pain to reduce the workload on the heart and decrease oxygen demand.
Question 5 of 5
A patient presents fully conscious with acute falciparum malaria following a visit to Nigeria. Which of the following treatments is most appropriate?
Correct Answer: B
Rationale: Acute falciparum malaria from Nigeria, a chloroquine-resistant area, requires effective therapy. Chloroquine is ineffective due to resistance. Proguanil/atovaquone (Malarone) treats uncomplicated falciparum malaria, rapid-acting and well-tolerated, most appropriate here. Primaquine targets liver stages, not acute blood infection. Pyrimethamine and hydroxychloroquine are less effective. Malarone's efficacy ensures rapid parasite clearance, vital in this potentially severe disease.