Penicillin can form a hapten-carrier conjugate with a self-protein that can then act as an immunogen and generate an immunoglobulin antibody, and can cross-react with a number of other antibiotics. This can complicate the treatment of bacterial infections in these patients because they are unable to take the antibiotics necessary to combat the infection.

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Pediatric Immunization NCLEX Questions Questions

Question 1 of 5

Penicillin can form a hapten-carrier conjugate with a self-protein that can then act as an immunogen and generate an immunoglobulin antibody, and can cross-react with a number of other antibiotics. This can complicate the treatment of bacterial infections in these patients because they are unable to take the antibiotics necessary to combat the infection.

Correct Answer: C

Rationale: This describes an IgE-mediated allergic response, where penicillin cross-reacts, causing hypersensitivity.

Question 2 of 5

If alternative processing uses the second polyadenylation site, then what type of heavy chain mRNA is derived?

Correct Answer: C

Rationale: Using the second polyadenylation site results in δ (delta) heavy chain mRNA, encoding IgD.

Question 3 of 5

Which of the following TCR genetic chains contain D-segments, similar to immunoglobulin heavy chains?

Correct Answer: C

Rationale: Beta (β) and delta (δ) chains contain D-segments, similar to immunoglobulin heavy chains.

Question 4 of 5

A TCR complex is comprised of the TCR, CD3 molecules, and which of the following CD3 chains?

Correct Answer: D

Rationale: The TCR complex includes two zeta ζ) chains as part of the CD3 signaling complex.

Question 5 of 5

Class III MHC genes encode for which of the following?

Correct Answer: C

Rationale: Class III MHC genes encode complement components, not T cells or cytokines.

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