ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
Pemphigus vulgaris
Correct Answer: D
Rationale: Pemphigus vulgaris is associated with HLA-DQ2.
Question 2 of 5
A protein of herpes simplex virus (HSV) binds to TAP and inhibits peptide transport into the endoplasmic reticulum. What is a consequence of this?
Correct Answer: A
Rationale: Inhibiting TAP prevents peptides from reaching the ER, reducing their expression on the cell surface via MHC Class I.
Question 3 of 5
Leukocyte-specific protein tyrosine kinase (Lck) is integral in the signaling cascade in cells. Zeta-chain-associated protein kinase 70 (ZAP-70), which binds CD3-zeta, is cell specific. Spleen tyrosine kinase (Syk), a signal transmitter, is found predominantly in cells.
Correct Answer: D
Rationale: Lck and ZAP-70 are T cell-specific (TCR signaling), while Syk is predominant in B cells (BCR signaling).
Question 4 of 5
Combat certain parasitic infections (e.g. worms); hydrolytic enzymes
Correct Answer: C
Rationale: Eosinophils target parasites with hydrolytic enzymes.
Question 5 of 5
The spleen, the major filter for blood, is about the size of a clenched fist and is found on the side associated posteriorly with ribs
Correct Answer: B
Rationale: The spleen is on the left side, posterior to ribs 9-11.