Patients under long use of glucocorticoids are advised NOT to:

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Introduction to the Pharmacology of CNS Drugs Questions

Question 1 of 5

Patients under long use of glucocorticoids are advised NOT to:

Correct Answer: A

Rationale: Glucocorticoids (e.g., prednisone) suppress the HPA axis with prolonged use, requiring gradual tapering to avoid adrenal insufficiency (choice A), a potentially fatal withdrawal effect. Monitoring blood glucose (choice B) is advised due to hyperglycemia risk. A potassium/calcium-rich diet (choice C) counters hypokalemia and osteoporosis. Salt reduction (choice D) manages fluid retention. Sudden cessation is the key precaution, emphasizing the need for tapering schedules to restore adrenal function safely.

Question 2 of 5

Type I diabetes mellitus:

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Sudden withdrawal of glucocorticoids after prolonged therapy results in:

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

A 47-year-old man exhibited signs and symptoms of acromegaly. Radiologic studies showed the presence of a large pituitary tumor. Which of the following drugs is most likely to be used as pharmacologic therapy?

Correct Answer: D

Rationale: Octreotide (choice D), a somatostatin analog, treats acromegaly by inhibiting growth hormone from pituitary tumors, reducing symptoms. Cosyntropin (choice A) tests adrenal function, Desmopressin (choice B) manages diabetes insipidus, Leuprolide (choice C) targets sex hormones. Octreotide is specific.

Question 5 of 5

A 12-year-old with newly diagnosed type I diabetes mellitus has ketoacidosis. Serum potassium level 3.5 mmol/L and PH 7.2. What are the lines of treatment?

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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