Pathogen-associated molecular patterns

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Pediatric Immunity NCLEX Questions Questions

Question 1 of 5

Pathogen-associated molecular patterns

Correct Answer: A

Rationale: PAMPs are conserved structures on various microorganisms, recognized by innate immunity.

Question 2 of 5

Regarding chemokines, which one of the following is the most accurate?

Correct Answer: C

Rationale: Chemokines, like IL-8, attract neutrophils to infection sites, aiding inflammation.

Question 3 of 5

Which of the following statements best applies to the following diagram?

Correct Answer: C

Rationale: MHC class I is expressed on all nucleated cells, including T and B cells. Answer assumed as C based on typical MHC I description.

Question 4 of 5

Which immune system cells recognize body cells with reduced expression of MHC class I molecules?

Correct Answer: D

Rationale: NK cells target cells with low MHC I, a sign of viral infection or malignancy.

Question 5 of 5

A 6-month-old presents with recurrent cellulitis and bacteremias due to Staphylococcus aureus. The white blood cell count is 2500 with 5% neutrophils, 10% eosinophils, 35% monocytes, and 50% lymphocytes. The platelet count is 650,000. A brother and a female cousin died at the age of 18 months and 2 years, respectively. The most likely diagnosis is

Correct Answer: C

Rationale: Kostmann disease (severe congenital neutropenia) fits with persistent neutropenia, recurrent Staphylococcus aureus infections, and a family history suggesting autosomal recessive inheritance.

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