ATI RN
Genetic Disorders in Pediatrics Questions
Question 1 of 5
Partial mole results from:
Correct Answer: C
Rationale: 2 maternal, 1 paternal sets (C) form a partial mole. Rationale: Triploidy (69, XXX or XXY) from dispermy or diploid egg retains some fetal tissue.
Question 2 of 5
Suppose there’s an X-linked recessive disease, if the mother has the disease, while the father doesn’t, what’s the chance that they’ll have an affected female?
Correct Answer: D
Rationale: Zero (D) chance for an affected female. Rationale: Mother (XX, affected, X^a X^a) and father (XY, unaffected, X^+ Y) produce sons (X^a Y, all affected) and daughters (X^a X^+, carriers). X-linked recessive requires two mutant alleles in females, impossible here.
Question 3 of 5
Matching: Vulvovaginitis - Nits on hair shaft
Correct Answer: C
Rationale: Nits on hair shafts indicate Pediculosis pubis (C, pubic lice). Rationale: Pinworms (A) are intestinal; Molluscum (B) causes skin lesions; Shigella (D) and Streptococcus (E) are bacterial, not associated with nits.
Question 4 of 5
Possible causes of vaginal bleeding in a prepubertal female include all of the following EXCEPT
Correct Answer: C
Rationale: Bleeding causes include steroids (A), foreign bodies (B), urethral prolapse (D), and neoplasms (E). Hemorrhagic cystitis (C) causes urinary, not vaginal, bleeding. Rationale: Cystitis affects the bladder; vaginal bleeding requires a genital source.
Question 5 of 5
Maternal exposure to DES places the female offspring at increased risk for
Correct Answer: B
Rationale: DES exposure in utero increases risk of clear cell adenocarcinoma of the vagina (B). Rationale: DES, a synthetic estrogen, causes vaginal epithelial changes; ovarian cancer (A) and other conditions (C, D) are not directly linked.