Parents with ill child came to the infectionist. They worked in one of the Asian countries for a long time. Child has eathy colored skin, loss of appetite, laxity, enlarged liver, spleen, peripheral glands. What protozoan illness can this child have?

Correct Answer: C

Rationale: The correct answer is C: Visceral leishmaniasis. This disease is caused by the protozoan parasite Leishmania, which is transmitted by sandfly bites. The symptoms described in the question, such as enlarged liver and spleen, peripheral gland enlargement, and eathy colored skin, are characteristic of visceral leishmaniasis. Amebiasis (choice A) typically presents with gastrointestinal symptoms, Balantidiasis (choice B) is caused by a different parasite and presents with dysentery, and Lambliasis (choice D) is caused by Giardia lamblia and presents with diarrhea.

Correct Answer: B

Rationale: The correct answer is B because the term "infectious process" refers to all biological processes that occur after the attachment and penetration of microbes into the host organism, regardless of whether there are clinical manifestations. This includes the colonization, multiplication, and spread of the microorganisms within the host. Explanation: A: Incorrect because it only mentions the attachment and penetration of microbes into the microorganism, missing the subsequent processes. C: Incorrect because it is too specific, stating that the penetration of microbes always manifests clinically, which is not always the case. D: Incorrect because there is a correct answer, which is B, as explained above.

Correct Answer: B

Rationale: The correct answer is B: Disinfection. Disinfection is not a method for food preservation but rather a process of destroying harmful microorganisms on surfaces. A: Pasteurization involves heating food to kill pathogens, preserving the food. C: Irradiation uses radiation to kill bacteria and parasites, extending shelf life. D: Ultrahigh-temperature pasteurization involves heating food at very high temperatures to extend shelf life. In summary, disinfection is not a method used to preserve food but rather to clean surfaces.

Correct Answer: D

Rationale: The correct answer is D: protozoan. Babesiosis is caused by a protozoan parasite called Babesia. Protozoans are single-celled organisms that can cause various diseases in humans. Babesiosis is transmitted to humans through the bite of infected ticks. Bacteria (choice A), viruses (choice B), and helminths (choice C) are not responsible for causing babesiosis. Bacteria are typically responsible for diseases like Lyme disease, viruses for illnesses like Zika, and helminths for infections such as parasitic worms. Thus, the correct choice for the causative agent of babesiosis is a protozoan.

Correct Answer: A

Rationale: The correct answer is A: Picornaviridae. Picornaviruses, such as enteroviruses, are commonly found in the feces of infected individuals. Therefore, their presence in water indicates fecal contamination and the need for additional purification. B: Herpesviridae are not typically associated with fecal contamination. C: Flaviviridae are mainly transmitted through arthropods like mosquitoes, not fecal contamination. D: Retroviridae, including HIV, are not typically excreted in high levels in feces and are not indicators of fecal contamination.

Correct Answer: A

Rationale: The correct answer is A: Bordetella pertussis. Bordetella pertussis is the bacterium responsible for causing whooping cough, also known as pertussis. It produces toxins that damage the respiratory tract, leading to severe coughing fits. Haemophilus influenzae, Streptococcus pneumoniae, and Mycobacterium tuberculosis are not associated with whooping cough. Haemophilus influenzae can cause respiratory infections but not whooping cough. Streptococcus pneumoniae is known for causing pneumonia, and Mycobacterium tuberculosis causes tuberculosis, both different from whooping cough. Therefore, the correct answer is A as it is the specific bacterium linked to the disease in question.

Correct Answer: C

Rationale: The correct answer is C: beaded. In an agar slant, beaded colonies appear as separate or semiconfluent, forming small, round colonies with gaps between them. This term accurately describes the appearance of the colonies in this context. A: Filiform colonies are dense and opaque with smooth edges, not separate or semiconfluent. B: Echinulate colonies have spiny projections, not the characteristic of separate or semiconfluent growth. D: Effuse colonies spread out extensively and lack defined borders, unlike the distinct appearance of separate or semiconfluent colonies.

Correct Answer: C

Rationale: The correct answer is C: Escherichia coli. E. coli is a gram-negative bacterium, which means it has an outer membrane containing lipopolysaccharides (LPS), also known as endotoxins. Endotoxins are released when the bacterium is destroyed, causing an inflammatory response. Streptococcus pneumoniae (choice A) is a gram-positive bacterium and does not produce endotoxins. Clostridium tetani (choice B) produces exotoxins, not endotoxins. Staphylococcus aureus (choice D) is also a gram-positive bacterium and does not produce endotoxins. In summary, E. coli is the correct answer because it is a gram-negative bacterium that produces endotoxins, while the other choices are gram-positive bacteria that do not produce endotoxins.

Correct Answer: C

Rationale: The correct answer is C: Macrolides or fluoroquinolones. Legionella pneumophila is a bacterium that causes Legionnaires' disease, a severe form of pneumonia. Macrolides (like azithromycin) and fluoroquinolones (like levofloxacin) are the recommended first-line treatments due to their ability to penetrate into lung tissues where Legionella infects. Penicillins and cephalosporins (choice A) are not effective against Legionella as it is intracellular and resistant to these antibiotics. Ethambutol and isoniazid (choice B) are used to treat tuberculosis, not Legionella infections. Second and third generation cephalosporins (choice D) are also not effective against Legionella. Therefore, the best choice for treating Legionella pneumophila infections is macrolides or fluoroquinolones.