ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 4
Parasitic worm eggs are resistant to low pH and proteolytic digestion in the stomach. Adult worms living inside the lower gut are protected from many of the components of the immune response. Mast cells respond to worms. What immunoglobulin activates these mast cells, leading to degranulation?
Correct Answer: C
Rationale: IgE is the key immunoglobulin involved in allergic and parasitic responses, binding to mast cells and triggering degranulation to combat worms.
Question 2 of 4
Subunit vaccines contains components from pathogens, which are inactivated and referred to as These vaccines are generally of low immunogenicity and may need to work effectively.
Correct Answer: D
Rationale: Subunit vaccines use toxoids or antigens and require adjuvants to boost immunogenicity.
Question 3 of 4
A patient in their early 20s presents with recurrent bacterial infections. Lab work shows B cells in the periphery as well as low immunoglobulin levels. History shows immunoglobulin levels have decreased with age. Which of the following is the most likely?
Correct Answer: D
Rationale: Common variable immunodeficiency (CVID) presents with low immunoglobulin levels and recurrent infections, often manifesting in young adults.
Question 4 of 4
A patient presents for a follow-up visit after a diagnosis of systemic lupus erythematosus (SLE). The physician suspects a misdiagnosis after finding immune complexes accumulated in the blood, lymph, and tissues. Which of the following is the most likely?
Correct Answer: C
Rationale: Early complement deficiencies (e.g., C1, C2, C4) lead to immune complex accumulation, mimicking SLE.