Pancreatic insufficiency, metaphyseal chondrodysplasia, autosomal recessive inheritance, defective chemotaxis, and neutropenia are features of

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Pediatric Immunity NCLEX Questions Questions

Question 1 of 5

Pancreatic insufficiency, metaphyseal chondrodysplasia, autosomal recessive inheritance, defective chemotaxis, and neutropenia are features of

Correct Answer: D

Rationale: Shwachman-Diamond syndrome includes pancreatic insufficiency, skeletal abnormalities, and neutropenia with defective chemotaxis.

Question 2 of 5

large family of molecules that stimulate leukocyte movement and regulate the migration of leukocytes from the blood to tissues and all of which are 8- to 12kD polypeptides, this definition best describes?

Correct Answer: B

Rationale: Chemokines are small (8-12 kDa) polypeptides that direct leukocyte migration and recruitment during immune responses.

Question 3 of 5

which of the following is a transcriptional factor for immune genes

Correct Answer: C

Rationale: NF-κB is a key transcription factor regulating immune gene expression, activated downstream of receptors like TLRs.

Question 4 of 5

Histamine releasing cell and contributes in hypersensitivity

Correct Answer: C

Rationale: Mast cells release histamine during hypersensitivity reactions like allergies.

Question 5 of 5

Monocytes move from the systemic circulatory system into general connective tissues, where they differentiate into what phagocytic cell type?

Correct Answer: A

Rationale: Monocytes differentiate into macrophages in tissues, functioning as phagocytes.

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