ATI RN
microbiology an introduction test bank Questions
Question 1 of 5
OSHA is a division of the
Correct Answer: C
Rationale: 1. OSHA stands for Occupational Safety and Health Administration. 2. OSHA is responsible for ensuring safe and healthy working conditions in the US. 3. The U.S. Department of Labor oversees OSHA's operations and regulations. 4. Therefore, the correct answer is C, as OSHA is a division of the U.S. Department of Labor. 5. Other choices are incorrect because they are not directly related to OSHA's jurisdiction or responsibilities.
Question 2 of 5
Which of the following is a phase I reaction in biotransformation?
Correct Answer: A
Rationale: The correct answer is A: Oxidation. Phase I reactions in biotransformation involve introducing or unmasking functional groups through oxidation, reduction, or hydrolysis. Oxidation reactions typically involve the addition of an oxygen atom or removal of hydrogen atoms, making them common phase I reactions. In this process, enzymes like cytochrome P450 play a crucial role in catalyzing the oxidation reactions. Conjugation (B), acetylation (C), and glucuronidation (D) are all examples of phase II reactions, which involve the conjugation of the drug or metabolite with endogenous compounds to increase water solubility for excretion. These reactions typically follow phase I reactions and are not classified as phase I reactions in biotransformation.
Question 3 of 5
The net gain of ATP molecules after the breakdown of one glucose molecule in glycolysis is
Correct Answer: B
Rationale: The correct answer is B (2). During glycolysis, one glucose molecule is broken down into two molecules of pyruvate. In this process, a net gain of 2 ATP molecules is produced through substrate-level phosphorylation. Specifically, ATP is generated during the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate and during the conversion of phosphoenolpyruvate to pyruvate. The other choices are incorrect because the net gain of ATP molecules in glycolysis is not 1, 3, or 4; it is 2 based on the specific enzymatic reactions involved in the pathway.
Question 4 of 5
A patient with pneumonia had sputum cultured on Endo agar, revealing red colonies. The bacteria were Gram-negative rods. What is the most likely causative agent?
Correct Answer: A
Rationale: Rationale for correct answer (A: Escherichia coli): 1. Endo agar selects for Gram-negative bacteria. 2. Red colonies on Endo agar indicate lactose fermentation, characteristic of E. coli. 3. E. coli is a common cause of pneumonia, especially in immunocompromised patients. Summary of why other choices are incorrect: - B: Klebsiella pneumoniae: Typically forms mucoid colonies on agar. - C: Pseudomonas aeruginosa: Produces characteristic greenish-blue colonies on agar. - D: Proteus mirabilis: Does not typically ferment lactose, so would not produce red colonies on Endo agar.
Question 5 of 5
Psychrophiles are also referred to as:
Correct Answer: A
Rationale: The correct answer is A: cryophiles. Psychrophiles are microorganisms that thrive in cold temperatures. The prefix "cryo-" means cold, which accurately describes the environment in which these organisms grow. Choice B, thermophiles, are organisms that thrive in high temperatures. Choice C, mesophiles, grow best at moderate temperatures. Choice D, psychrotrophs, are organisms that can grow at refrigeration temperatures but have an optimal growth temperature range different from psychrophiles.
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