Orthostatic hypotension can occur as a result of:

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Cardiovascular Drug Safety Pharmacology Questions

Question 1 of 5

Orthostatic hypotension can occur as a result of:

Correct Answer: D

Rationale: The correct answer is D: All of the above. Orthostatic hypotension can occur due to various mechanisms, such as central action of phenothiazines causing vasodilation, inhibition of norepinephrine uptake leading to decreased vasoconstriction, and alpha adrenoreceptor blockade reducing sympathetic response. Each of these factors can contribute to a drop in blood pressure upon standing. Choices A, B, and C all play a role in the development of orthostatic hypotension, making option D the correct comprehensive answer.

Question 2 of 5

Indicate the competitive antagonist of BZ receptors:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Flumazenil is a competitive antagonist of BZ receptors by binding and blocking their activity. 2. Buspirone is a partial agonist at serotonin receptors, not BZ receptors. 3. Picrotoxin is a non-competitive antagonist at GABA receptors, not BZ receptors. 4. Diazepam is a positive allosteric modulator at BZ receptors, not a competitive antagonist. Summary: Flumazenil is the correct answer as it specifically targets BZ receptors as a competitive antagonist, while the other options act on different receptors or in different ways.

Question 3 of 5

Which of the following inhalants is a gas anesthetic?

Correct Answer: C

Rationale: Certainly! Nitrous oxide is the correct answer as it is the only gas anesthetic listed. It is commonly used in dentistry and minor surgeries due to its anesthetic properties. Halothane, isoflurane, and desflurane are all liquid inhalants, not gas anesthetics. Nitrous oxide stands out as the only gas option among the choices.

Question 4 of 5

All of the following agents intensify the secretion of gastric glands EXCEPT:

Correct Answer: D

Rationale: The correct answer is D: Carbonate mineral waters. Carbonate mineral waters do not intensify the secretion of gastric glands. Pepsin is an enzyme that aids in digestion, Gastrin is a hormone that stimulates gastric acid secretion, and Histamine is a neurotransmitter that also stimulates gastric acid secretion. Carbonate mineral waters do not have the same effect on gastric glands as the other agents listed. Therefore, the correct answer is D.

Question 5 of 5

Indicate the drug belonging to antagonists of heparin:

Correct Answer: D

Rationale: The correct answer is D: Protamine sulfate. Protamine sulfate is an antagonist of heparin because it binds to heparin molecules, forming a stable complex that neutralizes the anticoagulant effects of heparin. This interaction helps to reverse the effects of heparin in cases of heparin overdose or when immediate cessation of anticoagulation is required. A: Aspirin is an antiplatelet agent that inhibits platelet aggregation by irreversibly inhibiting cyclooxygenase. It is not an antagonist of heparin. B: Dicumarol is a vitamin K antagonist that inhibits the synthesis of vitamin K-dependent clotting factors. It is not an antagonist of heparin. C: Dalteparin is a low-molecular-weight heparin that acts as an anticoagulant by inhibiting the activity of factor Xa. It is not an antagonist of heparin. In summary, Protamine sulfate

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