One of the following can cause thrombocytopenia with decreased megakaryocytes in bone marrow:

Correct Answer: B

Rationale: Aplastic anemia leads to a decrease in all blood cell lines, including megakaryocytes, unlike ITP and DIC, where platelet destruction occurs peripherally.

Correct Answer: A

Rationale: Prednisolone alone may be less effective for severe renal involvement.

Correct Answer: A

Rationale: Cataracts are not part of the CHARGE syndrome (Coloboma, Heart defects, Atresia choanae, Retardation, Genitourinary anomalies, Ear anomalies).

Correct Answer: D

Rationale: Allergic reactions are unpredictable and not dose-dependent, unlike drug toxicity and interactions.

Correct Answer: D

Rationale: Hepatobiliary scintigraphy assesses bile flow and is crucial for diagnosing biliary atresia, the most common cause of neonatal cholestasis.