ATI RN
Pharmacology Assessment 1 ATI Capstone Questions
Question 1 of 5
One hour after receiving intravenous morphine sulfate, a patient reports generalized itching. The nurse assesses the patient and notes clear breath sounds, no rash, respirations of 14 breaths per minute, a heart rate of 68 beats per minute, and a blood pressure of 110/70 mm Hg. Which action will the nurse take?
Correct Answer: D
Rationale: The correct action for the nurse to take in this situation is to prepare an epinephrine injection in case of an anaphylactic reaction. The patient's presentation of generalized itching could be a sign of an allergic reaction to morphine sulfate. It is important to be prepared for an anaphylactic reaction, which could potentially be life-threatening. Having epinephrine readily available allows for quick administration if needed to treat the allergic reaction. Reassuring the patient is also appropriate, but the priority in this situation is to be prepared for a possible serious allergic reaction. Administering naloxone to reverse opioid overdose is not indicated based on the patient's current vital signs and symptoms. Having resuscitation equipment available at the bedside is always a good practice, but preparing for an anaphylactic reaction takes precedence in this scenario.
Question 2 of 5
Name the four categories of enteral formulas? (Select all that apply.)
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Medications bound to protein have the following effect:
Correct Answer: C
Rationale: When medications are bound to proteins in the bloodstream, they are inactive and unable to exert their therapeutic effects. Only the unbound (free) fraction of the drug is pharmacologically active. Therefore, the more a drug is bound to protein, the less available it is for its desired effect. Protein binding also affects the drug's distribution and metabolism, but it does not enhance availability or increase liver metabolism. Rapid distribution to receptor sites is influenced by other factors, such as blood flow and tissue permeability.
Question 4 of 5
A student nurse was asked by the nurse instructor to explain the procedure for the administration of erythromycin ointment to the eyes of the newborn. Which of the following statements made by the student indicates a need for further research?
Correct Answer: D
Rationale: Flushing the newborn's eyes after instilling erythromycin ointment is incorrect because it would remove the medication, rendering it ineffective. The ointment is applied to the conjunctival sacs to prevent ophthalmia neonatorum, a bacterial infection that can occur during delivery. Cleaning the eyes before administration and applying the ointment within an hour after delivery are correct steps. Therefore, the statement about flushing the eyes indicates a need for further education.
Question 5 of 5
Which drug combination is recommended for chronic hepatitis C infection?
Correct Answer: C
Rationale: Chronic hepatitis C (HCV) treatment targets viral clearance. Pegylated interferon alfa boosts immunity, lamivudine treats HBV, not HCV, so that's incorrect. Adefovir also targets HBV, not HCV. Pegylated interferon alfa with ribavirin, an antiviral, is a historical standard for HCV, enhancing sustained virologic response across genotypes, the recommended combo. Adefovir/lamivudine suits HBV, oseltamivir/zanamivir influenza. Ribavirin's synergy with interferon was key before direct-acting antivirals, effective for this condition.