Once expressed on the surface of host cells, an MH

Question 1 of 5

Once expressed on the surface of host cells, an MHC protein remains stably associated with its bound peptide for several days. This highly stable peptide binding behavior is important because:

A. It prevents peptide exchanges on the cell surface, ensuring that peptide:MHC complexes are reliable indicators of the proteins present inside that host cell B. If the MHC protein lost its peptide it would become unstable, and would be rapidly internalized and degraded C. Pathogens would otherwise evade the immune response by making decoy peptides that mimic host cell peptides D. Pathogens would be able to evade the T cell response by making proteases that cleave MHC proteins inducing peptide release

Correct Answer: A

Rationale: Stable binding ensures MHC reflects intracellular proteins; instability occurs, but decoys or proteases are less relevant.

Question 2 of 5

Bacterial infections can cause a serious, potentially fatal systemic inflammatory response called

A. anaphylaxis B. pelvic inflammatory disease C. septic shock D. pneumonia

Correct Answer: C

Rationale: Septic shock is a systemic inflammatory response to bacterial infection, potentially fatal, unlike anaphylaxis (allergic), pelvic disease (local), or pneumonia (lung-specific).

Question 3 of 5

When an antigen-presenting cell interacts successfully with a helper T cell, the antigen-presenting cell secretes a signal molecule that assists in the activation of the helper T cell. This signal molecule is

A. interferon B. complement C. interleukin-1 D. perforin

Correct Answer: C

Rationale: Interleukin-1 from antigen-presenting cells (e.g., macrophages) activates helper T cells, unlike interferon, complement, or perforin (cytotoxic T cell product).

Question 4 of 5

Which of the following statements best describes the classical complement pathway effector function?

A. Inflammation B. Pathogenic lysis C. Opsonisation D. All of the above

Correct Answer: D

Rationale: The classical pathway, triggered by antibodies, promotes inflammation, lysis (via MAC), and opsonization (via C3b), making all options correct.

Question 5 of 5

Which of the statements below correctly describes Bcells and plasma cells?

A. Both are lymphocytes showing a high level of B cell receptor expression on their surface B. Both show little cytoplasm and a round nucleus C. Both show a large cytoplasm containing rough ER D. Plasma cells are differentiated B cells with the primary role of secreting antibodies

Correct Answer: D

Rationale: Plasma cells are B cell derivatives that secrete antibodies, with large cytoplasm and ER, unlike naÃ¯ve B cells.

Once expressed on the surface of host cells, an MHC protein remains stably associated with its bound peptide for several days. This highly stable peptide binding behavior is important because:

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