On the base of the clinical data a child was diagnosed with atypical pneumonia resistant to the effects of beta-lactam antibiotics. The patient's sputum was cultured and incubated in a special medium, which resulted in growth of microorganisms forming microscopic colonies with a dense center (looking like fried eggs). What microorganism caused the disease?

Correct Answer: A

Rationale: The correct answer is A: Mycoplasma pneumoniae. Mycoplasma pneumoniae is a common cause of atypical pneumonia and is known to be resistant to beta-lactam antibiotics. The description of microorganisms forming microscopic colonies with a dense center resembling fried eggs is characteristic of Mycoplasma pneumoniae colonies seen on special media. Summary of other choices: B: Klebsiella pneumoniae is not typically associated with atypical pneumonia and does not exhibit the described colony morphology. C: Streptococcus pneumoniae is not resistant to beta-lactam antibiotics and does not produce colonies with the described appearance. D: Legionella pneumophila is associated with Legionnaires' disease, not atypical pneumonia, and does not form colonies resembling fried eggs.

Correct Answer: A

Rationale: Step 1: Trichomonal gingivostomatitis is caused by the parasite Trichomonas tenax. Step 2: Metronidazole is the drug of choice for treating infections caused by anaerobic organisms like Trichomonas. Step 3: Metronidazole effectively targets and eliminates Trichomonas parasites in the oral cavity. Step 4: Therefore, the correct drug choice for treating trichomonal gingivostomatitis is Metronidazole. Summary: - Ampicillin (B) is an antibiotic effective against Gram-positive bacteria, not parasites. - Gentamicin sulfate (C) is an antibiotic used for bacterial infections, not parasitic infections. - Nystatin (D) is an antifungal medication used for treating fungal infections, not parasitic infections like trichomonal gingivostomatitis.

Correct Answer: D

Rationale: The correct answer is D because Cytomegalovirus infections are caused by human herpesvirus 5, also known as Human Herpesvirus 5 (HHV-5) or Cytomegalovirus (CMV). This virus belongs to the Herpesviridae family, genus Betaherpesvirinae. Options A, B, and C are incorrect as they do not correspond to the specific virus responsible for causing Cytomegalovirus infections.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. This bacteria is known for causing pneumonia due to its ability to infect the lungs and cause inflammation leading to pneumonia symptoms. It is a common cause of community-acquired pneumonia. Mycobacterium tuberculosis (B) causes tuberculosis, not pneumonia. Escherichia coli (C) is associated with urinary tract infections and gastrointestinal infections, not pneumonia. Pseudomonas aeruginosa (D) is known to cause infections in immunocompromised individuals but is not a common cause of pneumonia.

Correct Answer: A

Rationale: The correct answer is A: Klebsiella pneumoniae. This bacterium is commonly associated with pneumonia in elderly patients. Klebsiella pneumoniae is a Gram-negative, non-motile, rod-shaped bacterium that frequently causes pneumonia in individuals with underlying health conditions. It is known for its ability to produce a distinctive mucoid capsule. Pseudomonas aeruginosa (B) is more commonly associated with hospital-acquired infections, particularly in immunocompromised individuals. Escherichia coli (C) is a common cause of urinary tract infections but is less likely in this case due to the symptoms and sputum sample results. Haemophilus influenzae (D) is another common respiratory pathogen, but in this scenario, Klebsiella pneumoniae is the most likely causative agent based on the patient's age, symptoms, and the characteristics of the bacteria described in the sputum sample.

Correct Answer: B

Rationale: Rationale: The correct answer is B. Viruses of the family Paramyxoviridae cause the formation of giant multinucleated cells called syncytia. This occurs when infected cells fuse together, resulting in large, multinucleated structures. This is a characteristic cytopathic effect of paramyxoviruses. Summary: A: Fine grained degeneration is not typically seen in paramyxovirus infections. C: Large cell degeneration with grape clustering of cells is not a typical cytopathic effect of paramyxoviruses. D: Paramyxoviruses do provoke a cytopathic effect, so this statement is incorrect.

Correct Answer: A

Rationale: The correct answer is A: Serological. Serological testing involves analyzing blood samples for specific antibodies produced in response to the pertussis infection. This method can detect past infections by identifying the presence of antibodies against the pertussis bacteria in the blood. In this case, since the doctor suspects pertussis infection in both children, serological testing can confirm if they have been exposed to the bacteria. Summary: B: Biological testing does not specifically target pertussis antibodies in the blood. C: Bacteriological testing involves culturing bacteria from samples, which may not be as sensitive for retrospective diagnosis. D: Molecular biological testing focuses on genetic material of the bacteria, which may not provide direct evidence of past infection.

Correct Answer: D

Rationale: The correct answer is D: Multiplies by binary fission. Bacterial cells reproduce through binary fission, where a single cell divides into two identical daughter cells. This process is essential for bacterial growth and multiplication. A: The oxidative phosphorylation does not take place in the mitochondria of bacterial cells but in the cell membrane. B: Capsules are not organelles but outer protective layers found in some bacterial cells. C: Bacterial cells contain both DNA and RNA, essential for their genetic information and protein synthesis.

Correct Answer: C

Rationale: The correct answer is C: It is non-motile and non-spore forming. Pseudomonas aeruginosa is motile due to its flagella and is non-spore forming. A is correct because it is a Gram-negative bacterium, and B is correct as it is oxidase-positive. D is incorrect because C is not true.