On the base of the clinical data a child was diagnosed with atypical pneumonia resistant to the effects of beta-lactam antibiotics. The patient's sputum was cultured and incubated in a special medium, which resulted in growth of microorganisms forming microscopic colonies with a dense center (looking like fried eggs). What microorganism caused the disease?

Correct Answer: A

Rationale: The correct answer is A: Mycoplasma pneumoniae. Mycoplasma pneumoniae is a common cause of atypical pneumonia and is known to be resistant to beta-lactam antibiotics. The description of microorganisms forming microscopic colonies with a dense center resembling fried eggs is characteristic of Mycoplasma pneumoniae colonies seen on special media. Summary of other choices: B: Klebsiella pneumoniae is not typically associated with atypical pneumonia and does not exhibit the described colony morphology. C: Streptococcus pneumoniae is not resistant to beta-lactam antibiotics and does not produce colonies with the described appearance. D: Legionella pneumophila is associated with Legionnaires' disease, not atypical pneumonia, and does not form colonies resembling fried eggs.

Correct Answer: C

Rationale: The correct answer is C. Negri bodies are not associated with measles but with rabies. Step 1: Measles is a childhood infection with a rash (A). Step 2: Koplik spots are small white spots on a red base found inside the mouth and are characteristic of measles (B). Step 3: Negri bodies are eosinophilic cytoplasmic inclusions found in neurons infected with rabies virus, not measles (C). Step 4: Prophylaxis for measles is through the MMR vaccine, which is a live attenuated vaccine (D). Therefore, choice C is incorrect as it does not pertain to measles.

Correct Answer: C

Rationale: The correct answer is C: Prions. Prions are infectious proteins that lack nucleic acids, such as DNA or RNA, which are essential components of all other living organisms, including Archaea, Bacteria, and Viruses. Prions are unique in their ability to cause protein misfolding and aggregation in the brain, leading to various neurodegenerative diseases. The other choices (A: Archaea, B: Viruses, D: Bacteria) all contain nucleic acids in the form of DNA or RNA, making them distinct from prions. Therefore, C is the correct answer in this case.

Correct Answer: A

Rationale: The correct answer is A: Teratogenesis. Teratogenesis refers to the process of abnormal development of the fetus leading to congenital defects due to exposure to harmful agents during pregnancy. In this case, toxoplasmosis infection during pregnancy can lead to teratogenesis, causing multiple congenital defects in the child. Other choices are incorrect because B: Cancerogenesis refers to the process of cancer formation, C: Recombination is a genetic process unrelated to congenital defects, and D: Chemical mutagenesis refers to mutations caused by chemical agents, not necessarily congenital defects.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Arenaviridae family includes viruses with a segmented genome. 2. Lassa virus has a segmented genome, placing it in the Arenaviridae family. 3. Crimean-Congo hemorrhagic fever virus belongs to the Nairoviridae family, not Arenaviridae. 4. Rabies virus belongs to the Rhabdoviridae family, not Arenaviridae. 5. Epstein-Barr virus belongs to the Herpesviridae family, not Arenaviridae. Summary: A: Lassa virus is correct because it has a segmented genome, characteristic of Arenaviridae. B, C, D: Crimean-Congo hemorrhagic fever virus, Rabies virus, and Epstein-Barr virus belong to different virus families, not Arenaviridae.

Correct Answer: A

Rationale: The presence of flagella in a bacterial cell represents the H-antigen. Flagella are protein structures on the cell surface that play a role in bacterial motility. The H-antigen refers to the flagellar antigen, which is involved in immune responses and bacterial identification. Option A is correct because flagella are specifically associated with the H-antigen. Summarily, choices B and C are incorrect because the O-antigen and K-antigen are associated with lipopolysaccharide and capsule antigens, respectively, not flagella. Option D is incorrect as well because the correct association is with the H-antigen.

Correct Answer: A

Rationale: The correct answer is A because it lists the genera that belong to the family Reoviridae accurately. Orthoreovirus and Rotavirus are well-known genera within the family Reoviridae. Orbivirus is another genus belonging to the same family. Choice B is incorrect because Orthoretrovirus and Retrovirus are not part of the Reoviridae family. Orbfiloviridae is also not a valid genus within this family. Choice C is incorrect because Orthoretrovirus and Retrovirus are not part of the Reoviridae family. Orbivirus is the correct genus but the other two are inaccurate. Choice D is incorrect because Orthoretrovirus and Retrovirus are not part of the Reoviridae family. Orbarenaviridaefiloviridae is not a valid genus within Reoviridae.

Correct Answer: C

Rationale: In anaphase, sister chromatids separate and move towards opposite poles of the cell. This is facilitated by the shortening of microtubules attached to the centromeres. Prophase is the phase where chromosomes condense and the nuclear envelope breaks down. Metaphase is when chromosomes align at the metaphase plate. Telophase is when the nuclear envelope reforms and chromosomes decondense. Therefore, anaphase is the correct phase for chromatid separation.

Correct Answer: B

Rationale: The correct answer is B: biofilms. Biofilms are structured communities of microorganisms that adhere to a surface and are embedded in a matrix. This is the most appropriate term as it specifically describes the organization of various species into complex communities on a surface. Colonies (A) refer to groups of cells of the same species, not necessarily multiple species. Ecosystems (C) are broader systems involving interactions between living organisms and their environment. Plagues (D) are outbreaks of disease, not a term used to describe organized microbial communities.