ATI RN
Microbiology Chapter 12 Test Bank Questions
Question 1 of 5
On the 8th day since the patient was inoculated with antitetanic serum because of dirty wound of his foot he has developed rising temperature up to 380% , pains in the joints, rash and itch. The blood tests revealed leukopenia and thrombocytopenia. Allergic reaction of what type has developed in this case?
Correct Answer: D
Rationale: The correct answer is D: Immunocomplex. In this case, the patient's symptoms of fever, joint pains, rash, and itch along with leukopenia and thrombocytopenia indicate a serum sickness reaction. This is a type III hypersensitivity reaction where antigen-antibody complexes deposit in tissues, leading to inflammation and tissue damage. The symptoms typically occur 1-2 weeks after exposure to the antigen. Anaphylactic reaction (choice A) is immediate and involves IgE antibodies. Cytotoxic reaction (choice B) involves destruction of cells by antibodies. Delayed hypersensitivity (choice C) usually takes 48-72 hours to develop and involves T-cells. Therefore, the correct answer is D as it aligns with the symptoms and timeline of a type III hypersensitivity reaction.
Question 2 of 5
A family has two children. The younger child is under the year. The child has developed spastic cough attacks. Similar clinical presentation was observed in the elder preschool child one month ago. The doctor suspects pertussis infection. What method enables retrospective diagnostics of this disease?
Correct Answer: A
Rationale: The correct answer is A: Serological. Serological testing involves analyzing blood samples for specific antibodies produced in response to the pertussis infection. This method can detect past infections by identifying the presence of antibodies against the pertussis bacteria in the blood. In this case, since the doctor suspects pertussis infection in both children, serological testing can confirm if they have been exposed to the bacteria. Summary: B: Biological testing does not specifically target pertussis antibodies in the blood. C: Bacteriological testing involves culturing bacteria from samples, which may not be as sensitive for retrospective diagnosis. D: Molecular biological testing focuses on genetic material of the bacteria, which may not provide direct evidence of past infection.
Question 3 of 5
A 33 year old patient was delivered to the infectious diseases department on the 7-th day of disease. He complained about great weakness, high temperature, pain in the lumbar area and leg muscles, icteritiousness, dark color of urine, headache. The acute disease started with chill, body temperature rise up to 40oC, headache, pain in the lumbar area and sural muscles. Icterus turned up on the 4th day, nasal and scleral haemorrhages came on the 5th day. Fever has lasted for 6 days. Diuresis - 200 ml. What is the most probable diagnosis?
Correct Answer: A
Rationale: The most probable diagnosis is Leptospirosis. The symptoms described align with the classic presentation of Leptospirosis, such as fever, muscle pain, headache, jaundice, and hemorrhages. The initial symptoms of chills, high fever, and muscle pain followed by jaundice and hemorrhages are characteristic of Leptospirosis. The presence of dark urine and low diuresis also point towards kidney involvement, which is common in Leptospirosis due to renal failure. Additionally, the patient's history of potential exposure to contaminated water or soil supports the diagnosis, as Leptospirosis is commonly transmitted through contact with infected animal urine. Summary of other choices: - Typhoid fever typically presents with sustained fever, abdominal pain, and constipation, not matching the symptoms described. - Virus A hepatitis usually presents with jaundice, but other symptoms such as muscle pain and hemorrhages are not typical. - Sepsis is a systemic response
Question 4 of 5
Examination of duodenal contents revealed some pyriform protozoa with twin nuclei and four pairs of flagella. There were two supporting filaments between the nuclei and a suctorial disc on the ventral side. What representative of protozoa was revealed in this patient?
Correct Answer: D
Rationale: The correct answer is D: Intestinal trichomonad. This protozoan matches the description provided, with pyriform shape, twin nuclei, four pairs of flagella, supporting filaments, and a suctorial disc. Lamblia (A) lacks flagella and supporting filaments. Toxoplasma (B) is an intracellular parasite with different morphology. Leishmania (C) belongs to a different class with no flagella or supporting filaments. In summary, the unique combination of features described in the question points to an intestinal trichomonad, making it the correct answer.
Question 5 of 5
A patient consulted a dentist about itching and burning in the oral cavity; high temperature. The patient was diagnosed with trichomonal gingivostomatitis. What drug should be chosen for his treatment?
Correct Answer: A
Rationale: Step 1: Trichomonal gingivostomatitis is caused by the parasite Trichomonas tenax. Step 2: Metronidazole is the drug of choice for treating infections caused by anaerobic organisms like Trichomonas. Step 3: Metronidazole effectively targets and eliminates Trichomonas parasites in the oral cavity. Step 4: Therefore, the correct drug choice for treating trichomonal gingivostomatitis is Metronidazole. Summary: - Ampicillin (B) is an antibiotic effective against Gram-positive bacteria, not parasites. - Gentamicin sulfate (C) is an antibiotic used for bacterial infections, not parasitic infections. - Nystatin (D) is an antifungal medication used for treating fungal infections, not parasitic infections like trichomonal gingivostomatitis.