Of the following, the LEAST likely feature of Bernard-Soulier syndrome is

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Hematology Final Exam Questions Pdf Questions

Question 1 of 5

Of the following, the LEAST likely feature of Bernard-Soulier syndrome is

Correct Answer: B

Rationale: Bernard-Soulier syndrome (BSS) is autosomal recessive (A), with giant platelets (C), abnormal ristocetin (D), and transfusion as therapy (E). Severe thrombocytopenia (B) is less consistent, as counts are moderately low.

Question 2 of 5

The standard care for MOST children with severe hemophilia is

Correct Answer: A

Rationale: Prophylactic factor VIII (A) prevents bleeding and joint damage in severe hemophilia, superior to on-demand treatment (B) or avoidance measures alone (C, D, E).

Question 3 of 5

The LEAST indicator for an underlying hematological problem is

Correct Answer: B

Rationale: Fever (B) is less specific to hematology than pallor (A), petechiae (C), lymphadenopathy (D), or failure to thrive (E), which directly suggest anemia, bleeding, or marrow issues.

Question 4 of 5

A true hematological index for a cord blood sample is

Correct Answer: C

Rationale: Cord blood hemoglobin is typically 16-18 gm/dl (C); reticulocytes are higher (3-7%), leukocytes 9,000-30,000, and platelets 150,000-350,000.

Question 5 of 5

The LEAST helpful historical clue in the diagnosis of hemolytic anemia is

Correct Answer: D

Rationale: Chronic infection (D) is less specific to hemolysis than Mycoplasma (A), gallstones (B), or family history (C, E).

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