ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 9
Of the following salicylates, which does not exhibit an analgesic effects:
Correct Answer: C
Rationale: Salicylic acid, which is the parent compound of the salicylate drug class, does not exhibit analgesic effects. In order to have analgesic effects, such as pain relief, salicylic acid needs to be modified into derivatives like acetyl salicylic acid (aspirin), sodium salicylate, salicylamide, and diflunisal. These derivatives possess analgesic, antipyretic, and anti-inflammatory properties due to their ability to inhibit cyclooxygenase enzymes (COX) and subsequently decrease prostaglandin production.
Question 2 of 9
Which class of targeted therapy would cause the nurse the most concern in regard to a possible infusion reaction?
Correct Answer: C
Rationale: Monoclonal antibodies, such as trastuzumab and rituximab, are more likely to cause infusion reactions compared to other classes of targeted therapy. These reactions can range from mild symptoms like fever and chills to severe anaphylaxis. Tyrosine kinase inhibitors, multikinase inhibitors, and proteasome inhibitors are less commonly associated with infusion reactions. The nurse should closely monitor patients receiving monoclonal antibodies during infusion and be prepared to manage any adverse reactions promptly.
Question 3 of 9
What is the most important patient/family teaching for patients that are taking Digoxin
Correct Answer: D
Rationale: The most important patient teaching for patients taking Digoxin is to regularly monitor and take their pulse. Digoxin is a medication used to treat certain heart conditions by helping the heart beat stronger and more regularly. Monitoring the pulse is important because Digoxin can affect the heart rate, and if the pulse is too slow or irregular, it may indicate an adverse reaction to the medication. Patients should be taught how to check their pulse and to contact their healthcare provider if they notice any significant changes in their heart rate while taking Digoxin. Taking the pulse is crucial in ensuring the medication is being tolerated well and is working effectively.
Question 4 of 9
An 18-year-old college student is hanging shelves in his dorm room. He accidentally hits his thumb with the hammer, which subsequently becomes swollen and red. He takes some aspirin for the pain. Many enzymes and other proteins are activated in response to injury leading to inflammation. Production of which of the following mediators is inhibited by aspirin?
Correct Answer: D
Rationale: Aspirin reduces inflammation from injury. PGE2 , a prostaglandin, is inhibited by aspirin's COX blockade. HAT , IκB , and NF-κB are unrelated. NO isn't primarily affected. PGE2's reduction explains aspirin's analgesic and anti-inflammatory effects.
Question 5 of 9
Which patient would benefit from administration of simvastatin (Zocor) 80 mg?
Correct Answer: D
Rationale: A patient who has already been taking simvastatin (Zocor) for 12 months with no evidence of myopathy would benefit from administration of simvastatin 80 mg. This is because patients who have been on a stable dose of simvastatin without experiencing muscle-related side effects are considered to be tolerating the medication well. Increasing the dose to 80 mg may provide additional benefits in terms of lowering cholesterol levels without significant risk of myopathy.
Question 6 of 9
The nurse has a patient demonstrate self-administration of eyedrops. Place the steps in the order in which the patient will perform them.
Correct Answer: B
Rationale: The correct order for self-administering eyedrops is: 1. Wash hands (g). 2. Remove the cap (d). 3. Gently shake the bottle to evenly distribute the drug (b). 4. Tilt the head backward and look upward (e). 5. Pull the lower lid away from the eye so that a pouch is formed (a). 6. Place the dropper just above the pouch without touching the tip to the eye or finger (f). 7. Gently squeeze one drop of medicine into the pouch (h). 8. Press a finger against the inner corner of the eye for 2 to 3 minutes (c). This sequence ensures proper administration and minimizes the risk of contamination or systemic absorption.
Question 7 of 9
What type of diuretic is furosemide?
Correct Answer: A
Rationale: Furosemide is a loop diuretic. Loop diuretics act on the thick ascending limb of the loop of Henle in the kidney to inhibit sodium and chloride reabsorption, leading to increased excretion of water and electrolytes such as potassium and calcium. Loop diuretics are potent and are often used to treat conditions like edema, heart failure, and hypertension. Furosemide is commonly utilized to manage conditions such as congestive heart failure, high blood pressure, and edema associated with certain medical conditions.
Question 8 of 9
The client receives beclomethasone (Beconase) intranasally as treatment for allergic rhinitis. He asks the nurse if this drug is safe because it is a glucocorticoid. What is the best response by the nurse?
Correct Answer: A
Rationale: Beclomethasone, an intranasal corticosteroid, treats allergic rhinitis with minimal systemic absorption, reducing risks like adrenal suppression seen with oral steroids. The response 'Intranasal glucocorticoids produce almost no serious adverse effects' reassures the client accurately, as side effects (e.g., nasal irritation) are mild and rare. Swallowing isn't a significant concern due to low bioavailability. Prolonged use might increase minor risks (e.g., epistaxis), but isn't the primary safety factor. Once-daily use aligns with dosing but doesn't define safety. The nurse's best response (A) addresses the client's fear with evidence-based reassurance, emphasizing the drug's localized action and safety profile.
Question 9 of 9
A patient is being discharged on anticoagulant therapy. The nurse will include in the patient- education conversation that it is important to avoid herbal products that contain which substance?
Correct Answer: B
Rationale: Ginkgo is the herbal product to avoid because it can interact with anticoagulant therapy and increase the risk of bleeding. Ginkgo has blood-thinning properties, which can further potentiate the anticoagulant effects of medications like warfarin, increasing the risk of bleeding complications. It's essential for patients on anticoagulant therapy to avoid herbal products containing ginkgo to prevent adverse effects and ensure the effectiveness of their prescribed medication.